Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10845
MIM: 615611
HGNC: 2088
Ensembl: ENSG00000166855
Variants:
dbSNP: 10845
ClinVar: 10845
TCGA: ENSG00000166855
COSMIC: CLPX
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000166855 | ENST00000300107 | O76031 |
| ENSG00000166855 | ENST00000300107 | A0A024R5X7 |
| ENSG00000166855 | ENST00000559152 | H0YM48 |
| ENSG00000166855 | ENST00000559218 | H0YK07 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34704252 | 2021 | Heme-dependent recognition of 5-aminolevulinate synthase by the human mitochondrial molecular chaperone ClpX. | 3 |
| 34943861 | 2021 | Inactivity of Peptidase ClpP Causes Primary Accumulation of Mitochondrial Disaggregase ClpX with Its Interacting Nucleoid Proteins, and of mtDNA. | 7 |
| 34704252 | 2021 | Heme-dependent recognition of 5-aminolevulinate synthase by the human mitochondrial molecular chaperone ClpX. | 3 |
| 34943861 | 2021 | Inactivity of Peptidase ClpP Causes Primary Accumulation of Mitochondrial Disaggregase ClpX with Its Interacting Nucleoid Proteins, and of mtDNA. | 7 |
| 31059136 | 2020 | Experiencing community and domestic violence is associated with epigenetic changes in DNA methylation of BDNF and CLPX in adolescents. | 11 |
| 31059136 | 2020 | Experiencing community and domestic violence is associated with epigenetic changes in DNA methylation of BDNF and CLPX in adolescents. | 11 |
| 28874591 | 2017 | Mutation in human CLPX elevates levels of δ-aminolevulinate synthase and protoporphyrin IX to promote erythropoietic protoporphyria. | 41 |
| 28874591 | 2017 | Mutation in human CLPX elevates levels of δ-aminolevulinate synthase and protoporphyrin IX to promote erythropoietic protoporphyria. | 41 |
| 27389535 | 2016 | The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis. | 70 |
| 27389535 | 2016 | The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis. | 70 |
| 26142927 | 2015 | ClpX stimulates the mitochondrial unfolded protein response (UPRmt) in mammalian cells. | 36 |
| 26142927 | 2015 | ClpX stimulates the mitochondrial unfolded protein response (UPRmt) in mammalian cells. | 36 |
| 25083874 | 2014 | Stochastic but highly coordinated protein unfolding and translocation by the ClpXP proteolytic machine. | 78 |
| 25083874 | 2014 | Stochastic but highly coordinated protein unfolding and translocation by the ClpXP proteolytic machine. | 78 |
| 22710082 | 2012 | Substrate recognition and processing by a Walker B mutant of the human mitochondrial AAA+ protein CLPX. | 19 |
Citation
Dessen P
CLPX (caseinolytic mitochondrial matrix peptidase chaperone subunit X)
Atlas Genet Cytogenet Oncol Haematol. 2015-02-01
Online version: http://atlasgeneticsoncology.org/gene/55068/clpx-(caseinolytic-mitochondrial-matrix-peptidase-chaperone-subunit-x)
