POU3F3 (POU class 3 homeobox 3)

2015-02-01  

Identity

HGNC
LOCATION
2q12.1
LOCUSID
ALIAS
BRN1,OTF8,SNIBFIS,brain-1,oct-8

Other Information

Locus ID:

NCBI: 5455
MIM: 602480
HGNC: 9216
Ensembl: ENSG00000198914

Variants:

dbSNP: 5455
ClinVar: 5455
TCGA: ENSG00000198914
COSMIC: POU3F3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198914ENST00000361360P20264

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
371657522023POU3F3-related disorder: Defining the phenotype and expanding the molecular spectrum.2
371657522023POU3F3-related disorder: Defining the phenotype and expanding the molecular spectrum.2
336459212021Coexistence of severe developmental delay, epilepsy, and hemangioma in Snijders Blok-Fisher syndrome suggests the presence of a POU3F3-related SNIBFIS endophenotype: A case report.2
336459212021Coexistence of severe developmental delay, epilepsy, and hemangioma in Snijders Blok-Fisher syndrome suggests the presence of a POU3F3-related SNIBFIS endophenotype: A case report.2
322368212020Long Noncoding RNA POU3F3 and α-Synuclein in Plasma L1CAM Exosomes Combined with β-Glucocerebrosidase Activity: Potential Predictors of Parkinson's Disease.42
322368212020Long Noncoding RNA POU3F3 and α-Synuclein in Plasma L1CAM Exosomes Combined with β-Glucocerebrosidase Activity: Potential Predictors of Parkinson's Disease.42
308437712019LncRNA POU3F3 promotes proliferation and inhibits apoptosis of cancer cells in triple-negative breast cancer by inactivating caspase 9.24
313032652019De Novo Variants Disturbing the Transactivation Capacity of POU3F3 Cause a Characteristic Neurodevelopmental Disorder.21
308437712019LncRNA POU3F3 promotes proliferation and inhibits apoptosis of cancer cells in triple-negative breast cancer by inactivating caspase 9.24
313032652019De Novo Variants Disturbing the Transactivation Capacity of POU3F3 Cause a Characteristic Neurodevelopmental Disorder.21
265109062016Knockdown of linc-POU3F3 suppresses the proliferation, apoptosis, and migration resistance of colorectal cancer.33
265109062016Knockdown of linc-POU3F3 suppresses the proliferation, apoptosis, and migration resistance of colorectal cancer.33
254452822015Functional linc-POU3F3 is overexpressed and contributes to tumorigenesis in glioma.36
254452822015Functional linc-POU3F3 is overexpressed and contributes to tumorigenesis in glioma.36
246314942014Increased levels of the long intergenic non-protein coding RNA POU3F3 promote DNA methylation in esophageal squamous cell carcinoma cells.100

Citation

Dessen P

POU3F3 (POU class 3 homeobox 3)

Atlas Genet Cytogenet Oncol Haematol. 2015-02-01

Online version: http://atlasgeneticsoncology.org/gene/55071/pou3f3-(pou-class-3-homeobox-3)