VGLL1 (vestigial like family member 1)

2015-02-01  

Identity

HGNC
VGLL1
LOCATION
Xq26.3
LOCUSID
51442
ALIAS
TDU,VGL1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51442
MIM: 300583
HGNC: 20985
Ensembl: ENSG00000102243

Variants:

dbSNP: 51442
ClinVar: 51442
TCGA: ENSG00000102243
COSMIC: VGLL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000102243ENST00000370634Q99990
ENSG00000102243ENST00000440515H0Y5G3
ENSG00000102243ENST00000456412Q5H916

Expression (GTEx)

0
1
2
3
4
5
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
382333812024VGLL1 cooperates with TEAD4 to control human trophectoderm lineage specification.2
384176362024VGLL1 stabilization of cytoplasmic TAZ promotes EGFR expression and maintains tumor initiating cells in breast cancer independent of TEAD.0
382333812024VGLL1 cooperates with TEAD4 to control human trophectoderm lineage specification.2
384176362024VGLL1 stabilization of cytoplasmic TAZ promotes EGFR expression and maintains tumor initiating cells in breast cancer independent of TEAD.0
370049602023Vestigial-like 1 (VGLL1): An ancient co-transcriptional activator linking wing, placenta, and tumor development.2
370049602023Vestigial-like 1 (VGLL1): An ancient co-transcriptional activator linking wing, placenta, and tumor development.2
330697582021VGLL1 phosphorylation and activation promotes gastric cancer malignancy via TGF-β/ERK/RSK2 signaling.8
330697582021VGLL1 phosphorylation and activation promotes gastric cancer malignancy via TGF-β/ERK/RSK2 signaling.8
319257732020Novel EWSR1-VGLL1 fusion in a pediatric neuroepithelial neoplasm.4
330607902020A new perspective on the interaction between the Vg/VGLL1-3 proteins and the TEAD transcription factors.10
330876972020Vestigial-like 1 is a shared targetable cancer-placenta antigen expressed by pancreatic and basal-like breast cancers.8
319257732020Novel EWSR1-VGLL1 fusion in a pediatric neuroepithelial neoplasm.4
330607902020A new perspective on the interaction between the Vg/VGLL1-3 proteins and the TEAD transcription factors.10
330876972020Vestigial-like 1 is a shared targetable cancer-placenta antigen expressed by pancreatic and basal-like breast cancers.8
248914552014VGLL1 expression is associated with a triple-negative basal-like phenotype in breast cancer.32

Citation

Dessen P

VGLL1 (vestigial like family member 1)

Atlas Genet Cytogenet Oncol Haematol. 2015-02-01

Online version: http://atlasgeneticsoncology.org/gene/55078/vgll1-(vestigial-like-family-member-1)