GPR84 (G protein-coupled receptor 84)

2015-03-01  

Identity

HGNC
LOCATION
12q13.13
LOCUSID
ALIAS
EX33,GPCR4

Other Information

Locus ID:

NCBI: 53831
MIM: 606383
HGNC: 4535
Ensembl: ENSG00000139572

Variants:

dbSNP: 53831
ClinVar: 53831
TCGA: ENSG00000139572
COSMIC: GPR84

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000139572ENST00000267015Q9NQS5
ENSG00000139572ENST00000551809Q9NQS5

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (s) signalling eventsREACTOMER-HSA-418555
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
368698662024Function and regulation of GPR84 in human neutrophils.3
370853312024Regulation of the pro-inflammatory G protein-coupled receptor GPR84.1
375331662024GPR84 in physiology-Many functions in many tissues.0
368698662024Function and regulation of GPR84 in human neutrophils.3
370853312024Regulation of the pro-inflammatory G protein-coupled receptor GPR84.1
375331662024GPR84 in physiology-Many functions in many tissues.0
375431572023Kinetic insights into agonist-dependent signalling bias at the pro-inflammatory G-protein coupled receptor GPR84.1
375431572023Kinetic insights into agonist-dependent signalling bias at the pro-inflammatory G-protein coupled receptor GPR84.1
349686862022Hydroxycarboxylic acid receptor 3 and GPR84 - Two metabolite-sensing G protein-coupled receptors with opposing functions in innate immune cells.10
349686862022Hydroxycarboxylic acid receptor 3 and GPR84 - Two metabolite-sensing G protein-coupled receptors with opposing functions in innate immune cells.10
337892972021The Two Formyl Peptide Receptors Differently Regulate GPR84-Mediated Neutrophil NADPH Oxidase Activity.8
344974172021Inter-cellular CRISPR screens reveal regulators of cancer cell phagocytosis.60
337892972021The Two Formyl Peptide Receptors Differently Regulate GPR84-Mediated Neutrophil NADPH Oxidase Activity.8
344974172021Inter-cellular CRISPR screens reveal regulators of cancer cell phagocytosis.60
321026732020Natural biased signaling of hydroxycarboxylic acid receptor 3 and G protein-coupled receptor 84.9

Citation

Dessen P

GPR84 (G protein-coupled receptor 84)

Atlas Genet Cytogenet Oncol Haematol. 2015-03-01

Online version: http://atlasgeneticsoncology.org/gene/55088/chromosome-explorer/meetings/