Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 25874
MIM: 614737
HGNC: 24515
Ensembl: ENSG00000143158
Variants:
dbSNP: 25874
ClinVar: 25874
TCGA: ENSG00000143158
COSMIC: MPC2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36417180 | 2023 | MPC2 variants disrupt mitochondrial pyruvate metabolism and cause an early-onset mitochondriopathy. | 2 |
| 36417180 | 2023 | MPC2 variants disrupt mitochondrial pyruvate metabolism and cause an early-onset mitochondriopathy. | 2 |
| 33791391 | 2021 | Decreased Expression of MPC2 Contributes to Aerobic Glycolysis and Colorectal Cancer Proliferation by Activating mTOR Pathway. | 5 |
| 34664967 | 2021 | Structural Insights into the Human Mitochondrial Pyruvate Carrier Complexes. | 6 |
| 33791391 | 2021 | Decreased Expression of MPC2 Contributes to Aerobic Glycolysis and Colorectal Cancer Proliferation by Activating mTOR Pathway. | 5 |
| 34664967 | 2021 | Structural Insights into the Human Mitochondrial Pyruvate Carrier Complexes. | 6 |
| 32403431 | 2020 | Characteristic Analysis of Homo- and Heterodimeric Complexes of Human Mitochondrial Pyruvate Carrier Related to Metabolic Diseases. | 12 |
| 32664896 | 2020 | Mitochondrial pyruvate carrier: a potential target for diabetic nephropathy. | 4 |
| 32708919 | 2020 | The Multifaceted Pyruvate Metabolism: Role of the Mitochondrial Pyruvate Carrier. | 38 |
| 32403431 | 2020 | Characteristic Analysis of Homo- and Heterodimeric Complexes of Human Mitochondrial Pyruvate Carrier Related to Metabolic Diseases. | 12 |
| 32664896 | 2020 | Mitochondrial pyruvate carrier: a potential target for diabetic nephropathy. | 4 |
| 32708919 | 2020 | The Multifaceted Pyruvate Metabolism: Role of the Mitochondrial Pyruvate Carrier. | 38 |
| 29472561 | 2018 | Human mitochondrial pyruvate carrier 2 as an autonomous membrane transporter. | 26 |
| 29845198 | 2018 | Hypoxia induces lactate secretion and glycolytic efflux by downregulating mitochondrial pyruvate carrier levels in human umbilical vein endothelial cells. | 12 |
| 30087317 | 2018 | Genetic association and meta-analysis of a schizophrenia GWAS variant rs10489202 in East Asian populations. | 3 |
Citation
Dessen P
MPC2 (mitochondrial pyruvate carrier 2)
Atlas Genet Cytogenet Oncol Haematol. 2015-03-01
Online version: http://atlasgeneticsoncology.org/gene/55100/mpc2-(mitochondrial-pyruvate-carrier-2)
