Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6698
MIM: 182265
HGNC: 11259
Ensembl: ENSG00000169474
Variants:
dbSNP: 6698
ClinVar: 6698
TCGA: ENSG00000169474
COSMIC: SPRR1A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000169474 | ENST00000368762 | P35321 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Developmental Biology | REACTOME | R-HSA-1266738 |
| Keratinization | REACTOME | R-HSA-6805567 |
| Formation of the cornified envelope | REACTOME | R-HSA-6809371 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37468478 | 2023 | SPRR1A is a key downstream effector of MiR-150 during both maladaptive cardiac remodeling in mice and human cardiac fibroblast activation. | 0 |
| 37468478 | 2023 | SPRR1A is a key downstream effector of MiR-150 during both maladaptive cardiac remodeling in mice and human cardiac fibroblast activation. | 0 |
| 35263193 | 2022 | Small proline-rich protein 1A promotes lung adenocarcinoma progression and indicates unfavorable clinical outcomes. | 2 |
| 35768785 | 2022 | Survival-related indicators ALOX12B and SPRR1A are associated with DNA damage repair and tumor microenvironment status in HPV 16-negative head and neck squamous cell carcinoma patients. | 6 |
| 35263193 | 2022 | Small proline-rich protein 1A promotes lung adenocarcinoma progression and indicates unfavorable clinical outcomes. | 2 |
| 35768785 | 2022 | Survival-related indicators ALOX12B and SPRR1A are associated with DNA damage repair and tumor microenvironment status in HPV 16-negative head and neck squamous cell carcinoma patients. | 6 |
| 30652380 | 2019 | The combined use of EFS, GPX2, and SPRR1A expression could distinguish favorable from poor clinical outcome among epithelial-like head and neck carcinoma subtypes. | 8 |
| 30652380 | 2019 | The combined use of EFS, GPX2, and SPRR1A expression could distinguish favorable from poor clinical outcome among epithelial-like head and neck carcinoma subtypes. | 8 |
| 27304082 | 2017 | Expression of Cornified Envelope Proteins in Skin and Its Relationship with Atopic Dermatitis Phenotype. | 18 |
| 27304082 | 2017 | Expression of Cornified Envelope Proteins in Skin and Its Relationship with Atopic Dermatitis Phenotype. | 18 |
| 25424702 | 2015 | Clinical significance of SPRR1A expression in progesterone receptor-positive breast cancer. | 7 |
| 25424702 | 2015 | Clinical significance of SPRR1A expression in progesterone receptor-positive breast cancer. | 7 |
| 24886019 | 2014 | Clinical implications of SPRR1A expression in diffuse large B-cell lymphomas: a prospective, observational study. | 7 |
| 24886019 | 2014 | Clinical implications of SPRR1A expression in diffuse large B-cell lymphomas: a prospective, observational study. | 7 |
| 19672094 | 2010 | Locus 1q21 Gene expression changes in atopic dermatitis skin lesions: deregulation of small proline-rich region 1A. | 12 |
Citation
Dessen P
SPRR1A (small proline rich protein 1A)
Atlas Genet Cytogenet Oncol Haematol. 2015-03-01
Online version: http://atlasgeneticsoncology.org/gene/55116/sprr1a-(small-proline-rich-protein-1a)
