Identity
HGNC
LOCATION
1p35.1
LOCUSID
ALIAS
FRCP2,irisin
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 252995
MIM: 611906
HGNC: 20240
Ensembl: ENSG00000160097
Variants:
dbSNP: 252995
ClinVar: 252995
TCGA: ENSG00000160097
COSMIC: FNDC5
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000160097 | ENST00000373471 | A0A0A0MRR6 |
| ENSG00000160097 | ENST00000496770 | Q8NAU1 |
| ENSG00000160097 | ENST00000649537 | A0A3B3ITP1 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37815745 | 2024 | MiR-143-3p/FNDC5 axis: a novel regulator of insulin sensitivity. | 0 |
| 38043511 | 2024 | Relationship between Serum Irisin Level, All-Cause Mortality, and Cardiovascular Mortality in Peritoneal Dialysis Patients. | 1 |
| 38134742 | 2024 | Relationship of irisin with disease severity and dopamine uptake in Parkinson's disease patients. | 0 |
| 38218331 | 2024 | The role of irisin in kidney diseases. | 1 |
| 38309190 | 2024 | Role of irisin and myostatin on sarcopenia in malnourished patients diagnosed with GLIM criteria. | 2 |
| 38334669 | 2024 | The Role of FNDC5/Irisin in Cardiovascular Disease. | 3 |
| 38405155 | 2024 | The emerging roles of irisin in vascular calcification. | 1 |
| 38558303 | 2024 | FNDC5 inhibits malignant growth of human cervical cancer cells via restraining PI3K/AKT pathway. | 0 |
| 38591469 | 2024 | Irisin influences the in vitro differentiation of human mesenchymal stromal cells, promoting a tendency toward beiging adipogenesis. | 0 |
| 38788070 | 2024 | Plasma BDNF/Irisin Ratio Associates with Cognitive Function in Older People. | 0 |
| 38861537 | 2024 | Plasma irisin and the brain-derived neurotrophic factor levels in sedentary subjects: effect of 8-weeks lifestyle intervention. | 0 |
| 37815745 | 2024 | MiR-143-3p/FNDC5 axis: a novel regulator of insulin sensitivity. | 0 |
| 38043511 | 2024 | Relationship between Serum Irisin Level, All-Cause Mortality, and Cardiovascular Mortality in Peritoneal Dialysis Patients. | 1 |
| 38134742 | 2024 | Relationship of irisin with disease severity and dopamine uptake in Parkinson's disease patients. | 0 |
| 38218331 | 2024 | The role of irisin in kidney diseases. | 1 |
Citation
Dessen P
FNDC5 (fibronectin type III domain containing 5)
Atlas Genet Cytogenet Oncol Haematol. 2015-03-01
Online version: http://atlasgeneticsoncology.org/gene/55118/fndc5-(fibronectin-type-iii-domain-containing-5)
