ASCC2 (activating signal cointegrator 1 complex subunit 2)

2015-04-01   Dessen P  

Identity

HGNC
ASCC2
LOCATION
22q12.2
LOCUSID
84164
ALIAS
ASC1p100,p100
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 84164
MIM: 614216
HGNC: 24103
Ensembl: ENSG00000100325

Variants:

dbSNP: 84164
ClinVar: 84164
TCGA: ENSG00000100325
COSMIC: ASCC2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100325ENST00000307790Q9H1I8
ENSG00000100325ENST00000307790A0A024R1F9
ENSG00000100325ENST00000397771Q9H1I8
ENSG00000100325ENST00000397771A0A024R1F9
ENSG00000100325ENST00000411532H7C3Y4
ENSG00000100325ENST00000431535B1AH59
ENSG00000100325ENST00000449900F8WAQ6
ENSG00000100325ENST00000453160H7C395
ENSG00000100325ENST00000454854F2Z2W4
ENSG00000100325ENST00000458594F2Z2W4
ENSG00000100325ENST00000542393Q9H1I8

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
DNA RepairREACTOMER-HSA-73894
DNA Damage ReversalREACTOMER-HSA-73942
Reversal of alkylation damage by DNA dioxygenasesREACTOMER-HSA-73943
ALKBH3 mediated reversal of alkylation damageREACTOMER-HSA-112126

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
hippocampus
thyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil

References

Pubmed IDYearTitleCitations
336869582021Identification of key genes in coronary artery disease: an integrative approach based on weighted gene co-expression network analysis and their correlation with immune infiltration.12
336869582021Identification of key genes in coronary artery disease: an integrative approach based on weighted gene co-expression network analysis and their correlation with immune infiltration.12
331396972020The interaction of DNA repair factors ASCC2 and ASCC3 is affected by somatic cancer mutations.12
331396972020The interaction of DNA repair factors ASCC2 and ASCC3 is affected by somatic cancer mutations.12

Citation

Dessen P

ASCC2 (activating signal cointegrator 1 complex subunit 2)

Atlas Genet Cytogenet Oncol Haematol. 2015-04-01

Online version: http://atlasgeneticsoncology.org/gene/55161/ascc2-(activating-signal-cointegrator-1-complex-subunit-2)