Identity
HGNC
LOCATION
12q15
LOCUSID
ALIAS
99D8.1,CCT-beta,CCTB,HEL-S-100n,PRO1633,TCP-1-beta
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10576
MIM: 605139
HGNC: 1615
Ensembl: ENSG00000166226
Variants:
dbSNP: 10576
ClinVar: 10576
TCGA: ENSG00000166226
COSMIC: CCT2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38165547 | 2024 | CCT2 prevented β-catenin proteasomal degradation to sustain cancer stem cell traits and promote tumor progression in epithelial ovarian cancer. | 0 |
| 38165547 | 2024 | CCT2 prevented β-catenin proteasomal degradation to sustain cancer stem cell traits and promote tumor progression in epithelial ovarian cancer. | 0 |
| 31462707 | 2020 | Activating CCT2 triggers Gli-1 activation during hypoxic condition in colorectal cancer. | 25 |
| 31964905 | 2020 | Investigating Chaperonin-Containing TCP-1 subunit 2 as an essential component of the chaperonin complex for tumorigenesis. | 28 |
| 31462707 | 2020 | Activating CCT2 triggers Gli-1 activation during hypoxic condition in colorectal cancer. | 25 |
| 31964905 | 2020 | Investigating Chaperonin-Containing TCP-1 subunit 2 as an essential component of the chaperonin complex for tumorigenesis. | 28 |
| 29483666 | 2018 | Uncovering the genetic lesions underlying the most severe form of Hirschsprung disease by whole-genome sequencing. | 14 |
| 29483666 | 2018 | Uncovering the genetic lesions underlying the most severe form of Hirschsprung disease by whole-genome sequencing. | 14 |
| 27645772 | 2016 | CCT2 Mutations Evoke Leber Congenital Amaurosis due to Chaperone Complex Instability. | 17 |
| 27645772 | 2016 | CCT2 Mutations Evoke Leber Congenital Amaurosis due to Chaperone Complex Instability. | 17 |
| 25704758 | 2015 | Two members of the TRiC chaperonin complex, CCT2 and TCP1 are essential for survival of breast cancer cells and are linked to driving oncogenes. | 65 |
| 25704758 | 2015 | Two members of the TRiC chaperonin complex, CCT2 and TCP1 are essential for survival of breast cancer cells and are linked to driving oncogenes. | 65 |
| 24375412 | 2014 | Programmed cell death protein 5 interacts with the cytosolic chaperonin containing tailless complex polypeptide 1 (CCT) to regulate β-tubulin folding. | 19 |
| 24375412 | 2014 | Programmed cell death protein 5 interacts with the cytosolic chaperonin containing tailless complex polypeptide 1 (CCT) to regulate β-tubulin folding. | 19 |
| 23782473 | 2013 | Clinicopathological features and CCT2 and PDIA2 expression in gallbladder squamous/adenosquamous carcinoma and gallbladder adenocarcinoma. | 18 |
Citation
Dessen P
CCT2 (chaperonin containing TCP1 subunit 2)
Atlas Genet Cytogenet Oncol Haematol. 2015-05-01
Online version: http://atlasgeneticsoncology.org/gene/55185/cct2-(chaperonin-containing-tcp1-subunit-2)
