GALNT10 (polypeptide N-acetylgalactosaminyltransferase 10)

2015-05-01  

Identity

HGNC
LOCATION
5q33.2
LOCUSID
ALIAS
GALNACT10,PPGALNACT10,PPGANTASE10
FUSION GENES

Other Information

Locus ID:

NCBI: 55568
MIM: 608043
HGNC: 19873
Ensembl: ENSG00000164574

Variants:

dbSNP: 55568
ClinVar: 55568
TCGA: ENSG00000164574
COSMIC: GALNT10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164574ENST00000297107Q86SR1
ENSG00000164574ENST00000377661Q86SR1
ENSG00000164574ENST00000425427Q86SR1
ENSG00000164574ENST00000520647F2Z2M7

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Mucin type O-glycan biosynthesisKEGGko00512
Mucin type O-glycan biosynthesisKEGGhsa00512
Metabolic pathwaysKEGGhsa01100
O-glycan biosynthesis, mucin type coreKEGGhsa_M00056
O-glycan biosynthesis, mucin type coreKEGGM00056
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
O-linked glycosylationREACTOMER-HSA-5173105
O-linked glycosylation of mucinsREACTOMER-HSA-913709

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
333016052021The long noncoding RNA DLGAP1-AS2 facilitates cholangiocarcinoma progression via miR-505 and GALNT10.7
341114342021BAG3 epigenetically regulates GALNT10 expression via WDR5 and facilitates the stem cell-like properties of platin-resistant ovarian cancer cells.4
333016052021The long noncoding RNA DLGAP1-AS2 facilitates cholangiocarcinoma progression via miR-505 and GALNT10.7
341114342021BAG3 epigenetically regulates GALNT10 expression via WDR5 and facilitates the stem cell-like properties of platin-resistant ovarian cancer cells.4
318535762020Elevated GALNT10 expression identifies immunosuppressive microenvironment and dismal prognosis of patients with high grade serous ovarian cancer.16
332752282020GALNT10 promotes the proliferation and metastatic ability of gastric cancer and reduces 5-fluorouracil sensitivity by activating HOXD13.5
318535762020Elevated GALNT10 expression identifies immunosuppressive microenvironment and dismal prognosis of patients with high grade serous ovarian cancer.16
332752282020GALNT10 promotes the proliferation and metastatic ability of gastric cancer and reduces 5-fluorouracil sensitivity by activating HOXD13.5
281223582017Prognostic role of N-Acetylgalactosaminyltransferase 10 in metastatic renal cell carcinoma.2
281223582017Prognostic role of N-Acetylgalactosaminyltransferase 10 in metastatic renal cell carcinoma.2
253912662015Elevated Expression of N-Acetylgalactosaminyltransferase 10 Predicts Poor Survival and Early Recurrence of Patients with Clear-Cell Renal Cell Carcinoma.6
254223242015Decreased expression of hepatocyte nuclear factor 4α (Hnf4α)/microRNA-122 (miR-122) axis in hepatitis B virus-associated hepatocellular carcinoma enhances potential oncogenic GALNT10 protein activity.58
258980012015Genetic variants in LEKR1 and GALNT10 modulate sex-difference in carotid intima-media thickness: a genome-wide interaction study.13
253912662015Elevated Expression of N-Acetylgalactosaminyltransferase 10 Predicts Poor Survival and Early Recurrence of Patients with Clear-Cell Renal Cell Carcinoma.6
254223242015Decreased expression of hepatocyte nuclear factor 4α (Hnf4α)/microRNA-122 (miR-122) axis in hepatitis B virus-associated hepatocellular carcinoma enhances potential oncogenic GALNT10 protein activity.58

Citation

Dessen P

GALNT10 (polypeptide N-acetylgalactosaminyltransferase 10)

Atlas Genet Cytogenet Oncol Haematol. 2015-05-01

Online version: http://atlasgeneticsoncology.org/gene/55188/galnt10-(polypeptide-n-acetylgalactosaminyltransferase-10)