Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55127
HGNC: 25517
Ensembl: ENSG00000119285
Variants:
dbSNP: 55127
ClinVar: 55127
TCGA: ENSG00000119285
COSMIC: HEATR1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000119285 | ENST00000366579 | Q6P664 |
| ENSG00000119285 | ENST00000366581 | Q5T3Q7 |
| ENSG00000119285 | ENST00000366582 | Q9H583 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38225354 | 2024 | Ribogenesis boosts controlled by HEATR1-MYC interplay promote transition into brain tumour growth. | 0 |
| 38225354 | 2024 | Ribogenesis boosts controlled by HEATR1-MYC interplay promote transition into brain tumour growth. | 0 |
| 37247644 | 2023 | Nucleolar HEAT Repeat Containing 1 Up-regulated by the Mechanistic Target of Rapamycin Complex 1 Signaling Promotes Hepatocellular Carcinoma Growth by Dominating Ribosome Biogenesis and Proteome Homeostasis. | 1 |
| 37247644 | 2023 | Nucleolar HEAT Repeat Containing 1 Up-regulated by the Mechanistic Target of Rapamycin Complex 1 Signaling Promotes Hepatocellular Carcinoma Growth by Dominating Ribosome Biogenesis and Proteome Homeostasis. | 1 |
| 33894417 | 2021 | HEATR1, a novel interactor of Pontin/Reptin, stabilizes Pontin/Reptin and promotes cell proliferation of oral squamous cell carcinoma. | 3 |
| 33894417 | 2021 | HEATR1, a novel interactor of Pontin/Reptin, stabilizes Pontin/Reptin and promotes cell proliferation of oral squamous cell carcinoma. | 3 |
| 31785531 | 2020 | HEATR1 deficiency promotes pancreatic cancer proliferation and gemcitabine resistance by up-regulating Nrf2 signaling. | 12 |
| 32634230 | 2020 | HEATR1 promotes proliferation in gastric cancer in vitro and in vivo. | 1 |
| 31785531 | 2020 | HEATR1 deficiency promotes pancreatic cancer proliferation and gemcitabine resistance by up-regulating Nrf2 signaling. | 12 |
| 32634230 | 2020 | HEATR1 promotes proliferation in gastric cancer in vitro and in vivo. | 1 |
| 29143558 | 2018 | Perturbation of RNA Polymerase I transcription machinery by ablation of HEATR1 triggers the RPL5/RPL11-MDM2-p53 ribosome biogenesis stress checkpoint pathway in human cells. | 21 |
| 29143558 | 2018 | Perturbation of RNA Polymerase I transcription machinery by ablation of HEATR1 triggers the RPL5/RPL11-MDM2-p53 ribosome biogenesis stress checkpoint pathway in human cells. | 21 |
| 25126583 | 2014 | Glioma-associated antigen HEATR1 induces functional cytotoxic T lymphocytes in patients with glioma. | 19 |
| 25126583 | 2014 | Glioma-associated antigen HEATR1 induces functional cytotoxic T lymphocytes in patients with glioma. | 19 |
Citation
Dessen P
HEATR1 (HEAT repeat containing 1)
Atlas Genet Cytogenet Oncol Haematol. 2015-05-01
Online version: http://atlasgeneticsoncology.org/gene/55190/cancer-prone-explorer/
