Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4940
MIM: 603351
HGNC: 8088
Ensembl: ENSG00000111331
Variants:
dbSNP: 4940
ClinVar: 4940
TCGA: ENSG00000111331
COSMIC: OAS3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000111331 | ENST00000228928 | Q9Y6K5 |
| ENSG00000111331 | ENST00000546973 | H0YHL3 |
| ENSG00000111331 | ENST00000548514 | F8VS35 |
| ENSG00000111331 | ENST00000551007 | F8VWK9 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35305973 | 2022 | OAS1, OAS2, and OAS3 Contribute to Epidermal Keratinocyte Proliferation by Regulating Cell Cycle and Augmenting IFN-1‒Induced Jak1‒Signal Transducer and Activator of Transcription 1 Phosphorylation in Psoriasis. | 10 |
| 35934228 | 2022 | IFN-β1b induces OAS3 to inhibit EV71 via IFN-β1b/JAK/STAT1 pathway. | 4 |
| 36672782 | 2022 | Integrative Multiomics and Regulatory Network Analyses Uncovers the Role of OAS3, TRAFD1, miR-222-3p, and miR-125b-5p in Hepatitis E Virus Infection. | 4 |
| 35305973 | 2022 | OAS1, OAS2, and OAS3 Contribute to Epidermal Keratinocyte Proliferation by Regulating Cell Cycle and Augmenting IFN-1‒Induced Jak1‒Signal Transducer and Activator of Transcription 1 Phosphorylation in Psoriasis. | 10 |
| 35934228 | 2022 | IFN-β1b induces OAS3 to inhibit EV71 via IFN-β1b/JAK/STAT1 pathway. | 4 |
| 36672782 | 2022 | Integrative Multiomics and Regulatory Network Analyses Uncovers the Role of OAS3, TRAFD1, miR-222-3p, and miR-125b-5p in Hepatitis E Virus Infection. | 4 |
| 34031250 | 2021 | Zika virus employs the host antiviral RNase L protein to support replication factory assembly. | 8 |
| 34031250 | 2021 | Zika virus employs the host antiviral RNase L protein to support replication factory assembly. | 8 |
| 31006500 | 2020 | Protein and fat intake interacts with the haplotype of PTPN11_rs11066325, RPH3A_rs886477, and OAS3_rs2072134 to modulate serum HDL concentrations in middle-aged people. | 14 |
| 31629990 | 2020 | Length dependent activation of OAS proteins by dsRNA. | 12 |
| 32553473 | 2020 | Genetic analysis of a Taiwanese family identifies a DMRT3-OAS3 interaction that is involved in human sexual differentiation through the regulation of ESR1 expression. | 4 |
| 31006500 | 2020 | Protein and fat intake interacts with the haplotype of PTPN11_rs11066325, RPH3A_rs886477, and OAS3_rs2072134 to modulate serum HDL concentrations in middle-aged people. | 14 |
| 31629990 | 2020 | Length dependent activation of OAS proteins by dsRNA. | 12 |
| 32553473 | 2020 | Genetic analysis of a Taiwanese family identifies a DMRT3-OAS3 interaction that is involved in human sexual differentiation through the regulation of ESR1 expression. | 4 |
| 30078389 | 2019 | OAS1 and OAS3 negatively regulate the expression of chemokines and interferon-responsive genes in human macrophages. | 21 |
Citation
Dessen P
OAS3 (2-5-oligoadenylate synthetase 3)
Atlas Genet Cytogenet Oncol Haematol. 2015-05-01
Online version: http://atlasgeneticsoncology.org/gene/55214/oas3-(2-5-oligoadenylate-synthetase-3)
