PLA1A (phospholipase A1 member A)

2015-05-01  

Identity

HGNC
LOCATION
3q13.33
LOCUSID
ALIAS
PS-PLA1,PSPLA1

Other Information

Locus ID:

NCBI: 51365
MIM: 607460
HGNC: 17661
Ensembl: ENSG00000144837

Variants:

dbSNP: 51365
ClinVar: 51365
TCGA: ENSG00000144837
COSMIC: PLA1A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000144837ENST00000273371Q53H76
ENSG00000144837ENST00000475963H7C4H1
ENSG00000144837ENST00000488919Q53H76
ENSG00000144837ENST00000494440G5E9W0
ENSG00000144837ENST00000495992Q53H76

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Ras signaling pathwayKEGGhsa04014
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Phospholipid metabolismREACTOMER-HSA-1483257
Glycerophospholipid biosynthesisREACTOMER-HSA-1483206
Acyl chain remodelling of PSREACTOMER-HSA-1482801

References

Pubmed IDYearTitleCitations
353584722022Phosphatidylserine-Specific Phospholipase A1 Limits Aggressiveness of Lung Adenocarcinoma by Lysophosphatidylserine and Protein Kinase A-Dependent Pathway.2
353584722022Phosphatidylserine-Specific Phospholipase A1 Limits Aggressiveness of Lung Adenocarcinoma by Lysophosphatidylserine and Protein Kinase A-Dependent Pathway.2
337233502021PLA1A expression as a diagnostic marker of BRAF-mutant metastasis in melanoma cancer.4
348844862021Phospholipase A1 Member A Activates Fibroblast-like Synoviocytes through the Autotaxin-Lysophosphatidic Acid Receptor Axis.3
337233502021PLA1A expression as a diagnostic marker of BRAF-mutant metastasis in melanoma cancer.4
348844862021Phospholipase A1 Member A Activates Fibroblast-like Synoviocytes through the Autotaxin-Lysophosphatidic Acid Receptor Axis.3
319784062020Elevated phosphatidylserine-specific phospholipase A1 level in hyperthyroidism.5
320603562020Possible involvement of PS-PLA1 and lysophosphatidylserine receptor (LPS1) in hepatocellular carcinoma.5
319784062020Elevated phosphatidylserine-specific phospholipase A1 level in hyperthyroidism.5
320603562020Possible involvement of PS-PLA1 and lysophosphatidylserine receptor (LPS1) in hepatocellular carcinoma.5
311615542019Phosphatidylserine-Specific Phospholipase A1 is the Critical Bridge for Hepatitis C Virus Assembly.4
314687392019Serum phosphatidylserine-specific phospholipase A(1) as a novel biomarker for monitoring systemic lupus erythematosus disease activity.11
311615542019Phosphatidylserine-Specific Phospholipase A1 is the Critical Bridge for Hepatitis C Virus Assembly.4
314687392019Serum phosphatidylserine-specific phospholipase A(1) as a novel biomarker for monitoring systemic lupus erythematosus disease activity.11
295008642018Association between serum autotaxin or phosphatidylserine-specific phospholipase A1 levels and melanoma.7

Citation

Dessen P

PLA1A (phospholipase A1 member A)

Atlas Genet Cytogenet Oncol Haematol. 2015-05-01

Online version: http://atlasgeneticsoncology.org/gene/55217/pla1a-(phospholipase-a1-member-a)