Identity
HGNC
LOCATION
19q13.41
LOCUSID
ALIAS
PRO940,SIGLEC-10,SLG2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 89790
MIM: 606091
HGNC: 15620
Ensembl: ENSG00000142512
Variants:
dbSNP: 89790
ClinVar: 89790
TCGA: ENSG00000142512
COSMIC: SIGLEC10
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Adaptive Immune System | REACTOME | R-HSA-1280218 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | REACTOME | R-HSA-198933 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38401023 | 2024 | Gene expression patterns of CRYM and SIGLEC10 in Alzheimer's disease: potential early diagnostic indicators. | 0 |
| 38423652 | 2024 | Siglec10 Expression on Tumor-associated Macrophages Is an Independent Prognostic Factor in Stage I Lung Adenocarcinoma. | 0 |
| 38401023 | 2024 | Gene expression patterns of CRYM and SIGLEC10 in Alzheimer's disease: potential early diagnostic indicators. | 0 |
| 38423652 | 2024 | Siglec10 Expression on Tumor-associated Macrophages Is an Independent Prognostic Factor in Stage I Lung Adenocarcinoma. | 0 |
| 37933581 | 2023 | High Expression and Significance of Siglec10/CD24 in Unexplained Missed Abortion. | 0 |
| 37933581 | 2023 | High Expression and Significance of Siglec10/CD24 in Unexplained Missed Abortion. | 0 |
| 35075579 | 2022 | Innate immune checkpoint Siglec10 in cancers: mining of comprehensive omics data and validation in patient samples. | 6 |
| 36188429 | 2022 | Long-Term Elevated Siglec-10 in Cerebral Spinal Fluid Heralds Better Prognosis for Patients with Aneurysmal Subarachnoid Hemorrhage. | 0 |
| 35075579 | 2022 | Innate immune checkpoint Siglec10 in cancers: mining of comprehensive omics data and validation in patient samples. | 6 |
| 36188429 | 2022 | Long-Term Elevated Siglec-10 in Cerebral Spinal Fluid Heralds Better Prognosis for Patients with Aneurysmal Subarachnoid Hemorrhage. | 0 |
| 32790899 | 2021 | Novel insights into the function of CD24: A driving force in cancer. | 81 |
| 33223341 | 2021 | A Guillain-Barré syndrome-associated SIGLEC10 rare variant impairs its recognition of gangliosides. | 7 |
| 32790899 | 2021 | Novel insights into the function of CD24: A driving force in cancer. | 81 |
| 33223341 | 2021 | A Guillain-Barré syndrome-associated SIGLEC10 rare variant impairs its recognition of gangliosides. | 7 |
| 32046870 | 2020 | Siglec-10 expression is up-regulated in activated human CD4(+) T cells. | 10 |
Citation
Dessen P
SIGLEC10 (sialic acid binding Ig like lectin 10)
Atlas Genet Cytogenet Oncol Haematol. 2015-05-01
Online version: http://atlasgeneticsoncology.org/gene/55220/siglec10-(sialic-acid-binding-ig-like-lectin-10)
