Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10736
MIM: 604994
HGNC: 10888
Ensembl: ENSG00000170577
Variants:
dbSNP: 10736
ClinVar: 10736
TCGA: ENSG00000170577
COSMIC: SIX2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000170577 | ENST00000303077 | Q9NPC8 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37461228 | 2024 | NIK-mediated reactivation of SIX2 enhanced the CSC-like traits of hepatocellular carcinoma cells through suppressing ubiquitin-proteasome system. | 1 |
| 37461228 | 2024 | NIK-mediated reactivation of SIX2 enhanced the CSC-like traits of hepatocellular carcinoma cells through suppressing ubiquitin-proteasome system. | 1 |
| 35913414 | 2022 | De novo SIX2 activation in human kidneys treated with neonatal kidney stem/progenitor cells. | 5 |
| 35913414 | 2022 | De novo SIX2 activation in human kidneys treated with neonatal kidney stem/progenitor cells. | 5 |
| 33281191 | 2021 | Analysis of the mutational status of SIX1/2 and microRNA processing genes in paired primary and relapsed Wilms tumors and association with relapse. | 5 |
| 33281191 | 2021 | Analysis of the mutational status of SIX1/2 and microRNA processing genes in paired primary and relapsed Wilms tumors and association with relapse. | 5 |
| 32460030 | 2020 | SIX2 Regulates Human β Cell Differentiation from Stem Cells and Functional Maturation In Vitro. | 25 |
| 32506814 | 2020 | Maternal SLE and brachytelephalangic chondrodysplasia punctata in a patient with unrelated de novo RAF1 and SIX2 variants. | 0 |
| 33334785 | 2020 | Overexpression of Sine Oculis Homeobox Homolog 2 Predicts Poor Survival and Clinical Parameters of Patients with Colon Adenocarcinoma. | 0 |
| 32460030 | 2020 | SIX2 Regulates Human β Cell Differentiation from Stem Cells and Functional Maturation In Vitro. | 25 |
| 32506814 | 2020 | Maternal SLE and brachytelephalangic chondrodysplasia punctata in a patient with unrelated de novo RAF1 and SIX2 variants. | 0 |
| 33334785 | 2020 | Overexpression of Sine Oculis Homeobox Homolog 2 Predicts Poor Survival and Clinical Parameters of Patients with Colon Adenocarcinoma. | 0 |
| 30606720 | 2019 | SIX2 Mediates Late-Stage Metastasis via Direct Regulation of SOX2 and Induction of a Cancer Stem Cell Program. | 21 |
| 30894749 | 2019 | A NIK-SIX signalling axis controls inflammation by targeted silencing of non-canonical NF-κB. | 27 |
| 31090452 | 2019 | PPARG Negatively Modulates Six2 in Tumor Formation of Clear Cell Renal Cell Carcinoma. | 10 |
Citation
Dessen P
SIX2 (SIX homeobox 2)
Atlas Genet Cytogenet Oncol Haematol. 2015-05-01
Online version: http://atlasgeneticsoncology.org/gene/55221/six2-(six-homeobox-2)
