TRIM15 (tripartite motif containing 15)

2015-05-01  

Identity

HGNC
LOCATION
6p22.1
LOCUSID
ALIAS
RNF93,ZNF178,ZNFB7
FUSION GENES

Other Information

Locus ID:

NCBI: 89870
HGNC: 16284
Ensembl: ENSG00000204610

Variants:

dbSNP: 89870
ClinVar: 89870
TCGA: ENSG00000204610
COSMIC: TRIM15

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000204610ENST00000376688Q9C019
ENSG00000204610ENST00000376694Q9C019
ENSG00000204610ENST00000376694Q5SRL0
ENSG00000204610ENST00000433744H0Y5R0
ENSG00000204610ENST00000619857A0A087X199

Expression (GTEx)

0
5
10
15

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
366700972023TRIM15 forms a regulatory loop with the AKT/FOXO1 axis and LASP1 to modulate the sensitivity of HCC cells to TKIs.2
366700972023TRIM15 forms a regulatory loop with the AKT/FOXO1 axis and LASP1 to modulate the sensitivity of HCC cells to TKIs.2
355348962022E3 ligase TRIM15 facilitates non-small cell lung cancer progression through mediating Keap1-Nrf2 signaling pathway.10
355348962022E3 ligase TRIM15 facilitates non-small cell lung cancer progression through mediating Keap1-Nrf2 signaling pathway.10
335153452021Knockdown of TRIM15 inhibits the proliferation, migration and invasion of esophageal squamous cell carcinoma cells through inactivation of the Wnt/β-catenin signaling pathway.4
344973682021TRIM15 and CYLD regulate ERK activation via lysine-63-linked polyubiquitination.31
335153452021Knockdown of TRIM15 inhibits the proliferation, migration and invasion of esophageal squamous cell carcinoma cells through inactivation of the Wnt/β-catenin signaling pathway.4
344973682021TRIM15 and CYLD regulate ERK activation via lysine-63-linked polyubiquitination.31
304125182018TRIM15 Exerts Anti-Tumor Effects Through Suppressing Cancer Cell Invasion in Gastric Adenocarcinoma.10
304125182018TRIM15 Exerts Anti-Tumor Effects Through Suppressing Cancer Cell Invasion in Gastric Adenocarcinoma.10
254509702015Role of the focal adhesion protein TRIM15 in colon cancer development.25
254509702015Role of the focal adhesion protein TRIM15 in colon cancer development.25
250152962014TRIM15 is a focal adhesion protein that regulates focal adhesion disassembly.14
250152962014TRIM15 is a focal adhesion protein that regulates focal adhesion disassembly.14
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

TRIM15 (tripartite motif containing 15)

Atlas Genet Cytogenet Oncol Haematol. 2015-05-01

Online version: http://atlasgeneticsoncology.org/gene/55228/trim15-(tripartite-motif-containing-15)