Identity
HGNC
LOCATION
21q22.3
LOCUSID
ALIAS
APMR4,CTRCT44,HYPT14,OSC
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4047
MIM: 600909
HGNC: 6708
Ensembl: ENSG00000160285
Variants:
dbSNP: 4047
ClinVar: 4047
TCGA: ENSG00000160285
COSMIC: LSS
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37628669 | 2023 | LSS rs2254524 Increases the Risk of Hypertension in Children and Adolescents with Obesity. | 0 |
| 37628669 | 2023 | LSS rs2254524 Increases the Risk of Hypertension in Children and Adolescents with Obesity. | 0 |
| 33222230 | 2021 | Novel mutations in Chinese hypotrichosis simplex patients associated with LSS gene. | 5 |
| 34318586 | 2021 | Four hypotrichosis families with mutations in the gene LSS presenting with and without neurodevelopmental phenotypes. | 5 |
| 33222230 | 2021 | Novel mutations in Chinese hypotrichosis simplex patients associated with LSS gene. | 5 |
| 34318586 | 2021 | Four hypotrichosis families with mutations in the gene LSS presenting with and without neurodevelopmental phenotypes. | 5 |
| 32101538 | 2020 | Metabolic and pathologic profiles of human LSS deficiency recapitulated in mice. | 12 |
| 32877255 | 2020 | The Polymorphism rs2968 of LSS Gene Confers Susceptibility to Age-Related Cataract. | 6 |
| 32101538 | 2020 | Metabolic and pathologic profiles of human LSS deficiency recapitulated in mice. | 12 |
| 32877255 | 2020 | The Polymorphism rs2968 of LSS Gene Confers Susceptibility to Age-Related Cataract. | 6 |
| 30723320 | 2019 | Biallelic pathogenic variants in the lanosterol synthase gene LSS involved in the cholesterol biosynthesis cause alopecia with intellectual disability, a rare recessive neuroectodermal syndrome. | 15 |
| 30923116 | 2019 | Target identification reveals lanosterol synthase as a vulnerability in glioma. | 27 |
| 31322293 | 2019 | A novel and a known mutation in LSS gene associated with hypotrichosis 14 in a Chinese family. | 3 |
| 30723320 | 2019 | Biallelic pathogenic variants in the lanosterol synthase gene LSS involved in the cholesterol biosynthesis cause alopecia with intellectual disability, a rare recessive neuroectodermal syndrome. | 15 |
| 30923116 | 2019 | Target identification reveals lanosterol synthase as a vulnerability in glioma. | 27 |
Citation
Dessen P
LSS (lanosterol synthase)
Atlas Genet Cytogenet Oncol Haematol. 2015-06-01
Online version: http://atlasgeneticsoncology.org/gene/55266/lss-(lanosterol-synthase)
