FCGRT (Fc fragment of IgG receptor and transporter)

2015-06-01  

Identity

HGNC
FCGRT
LOCATION
19q13.33
LOCUSID
2217
ALIAS
FCRN,alpha-chain
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 2217
MIM: 601437
HGNC: 3621
Ensembl: ENSG00000104870

Variants:

dbSNP: 2217
ClinVar: 2217
TCGA: ENSG00000104870
COSMIC: FCGRT

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000104870ENST00000221466P55899
ENSG00000104870ENST00000221466A0A024QZI2
ENSG00000104870ENST00000426395P55899
ENSG00000104870ENST00000426395A0A024QZI2
ENSG00000104870ENST00000593381M0R220
ENSG00000104870ENST00000596975M0R0A9
ENSG00000104870ENST00000598076M0R0H0
ENSG00000104870ENST00000598319M0QYN1
ENSG00000104870ENST00000598491M0R266
ENSG00000104870ENST00000598927M0QYN9
ENSG00000104870ENST00000599701M0R2T3
ENSG00000104870ENST00000599988M0R0K7
ENSG00000104870ENST00000600273M0QYM4

Expression (GTEx)

0
50
100
150
200
250
300
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
382058882024Association of the neonatal Fc receptor promoter variable number of tandem repeat polymorphism with immunoglobulin response in patients with chronic inflammatory demyelinating polyneuropathy.1
383531272024Albumin influences leucocyte FcRn expression in the early days of kidney transplantation.0
382058882024Association of the neonatal Fc receptor promoter variable number of tandem repeat polymorphism with immunoglobulin response in patients with chronic inflammatory demyelinating polyneuropathy.1
383531272024Albumin influences leucocyte FcRn expression in the early days of kidney transplantation.0
367260332023The therapeutic age of the neonatal Fc receptor.23
367260332023The therapeutic age of the neonatal Fc receptor.23
347537972022An Expanded Genome-Wide Association Study of Fructosamine Levels Identifies RCN3 as a Replicating Locus and Implicates FCGRT as the Effector Transcript.1
349969502022Human IgE does not bind to human FcRn.1
358627852022Human FcRn Is a Two-in-One Attachment-Uncoating Receptor for Echovirus 18.2
347537972022An Expanded Genome-Wide Association Study of Fructosamine Levels Identifies RCN3 as a Replicating Locus and Implicates FCGRT as the Effector Transcript.1
349969502022Human IgE does not bind to human FcRn.1
358627852022Human FcRn Is a Two-in-One Attachment-Uncoating Receptor for Echovirus 18.2
333600962021Demonstration of fibrinogen-FcRn binding at acidic pH by means of Fluorescence Correlation Spectroscopy.2
346349602021Neonatal Fc receptor expression in lymphoid and myeloid cells in systemic lupus erythematosus.3
347044152021Research progress on neonatal Fc receptor and its application.1

Citation

Dessen P

FCGRT (Fc fragment of IgG receptor and transporter)

Atlas Genet Cytogenet Oncol Haematol. 2015-06-01

Online version: http://atlasgeneticsoncology.org/gene/55268/fcgrt-(fc-fragment-of-igg-receptor-and-transporter)