Identity
HGNC
LOCATION
2q37.3
LOCUSID
ALIAS
ILKAP2,ILKAP3,PP2C-DELTA,PP2CD,PPM1O
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 80895
MIM: 618909
HGNC: 15566
Ensembl: ENSG00000132323
Variants:
dbSNP: 80895
ClinVar: 80895
TCGA: ENSG00000132323
COSMIC: ILKAP
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447288 | Essential hypertension | Disease | ClinicalAnnotation | associated | PD | ||
| PA449899 | hydrochlorothiazide | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38379270 | 2024 | ILKAP Promotes the Metastasis of Hepatocellular Carcinoma Cells by Inhibiting β-Catenin Degradation and Enhancing the WNT Signaling Pathway. | 0 |
| 38379270 | 2024 | ILKAP Promotes the Metastasis of Hepatocellular Carcinoma Cells by Inhibiting β-Catenin Degradation and Enhancing the WNT Signaling Pathway. | 0 |
| 29742494 | 2018 | ILKAP Binding to and Dephosphorylating HIF-1α is Essential for Apoptosis Induced by Severe Hypoxia. | 1 |
| 29742494 | 2018 | ILKAP Binding to and Dephosphorylating HIF-1α is Essential for Apoptosis Induced by Severe Hypoxia. | 1 |
| 25872452 | 2015 | Endometrial ILKAP expression among patients with endometriosis and its association with clinical characteristics. | 0 |
| 26460618 | 2015 | ILKAP, ILK and PINCH1 control cell survival of p53-wildtype glioblastoma cells after irradiation. | 8 |
| 25872452 | 2015 | Endometrial ILKAP expression among patients with endometriosis and its association with clinical characteristics. | 0 |
| 26460618 | 2015 | ILKAP, ILK and PINCH1 control cell survival of p53-wildtype glioblastoma cells after irradiation. | 8 |
| 24743186 | 2014 | Involvement of ANXA5 and ILKAP in susceptibility to malignant melanoma. | 5 |
| 24743186 | 2014 | Involvement of ANXA5 and ILKAP in susceptibility to malignant melanoma. | 5 |
| 23329845 | 2013 | Characterization of nuclear localization signal in the N terminus of integrin-linked kinase-associated phosphatase (ILKAP) and its essential role in the down-regulation of RSK2 protein signaling. | 5 |
| 23329845 | 2013 | Characterization of nuclear localization signal in the N terminus of integrin-linked kinase-associated phosphatase (ILKAP) and its essential role in the down-regulation of RSK2 protein signaling. | 5 |
| 21782789 | 2011 | Palladin is a novel binding partner of ILKAP in eukaryotic cells. | 4 |
| 21782789 | 2011 | Palladin is a novel binding partner of ILKAP in eukaryotic cells. | 4 |
Citation
Dessen P
ILKAP (ILK associated serine/threonine phosphatase)
Atlas Genet Cytogenet Oncol Haematol. 2015-06-01
Online version: http://atlasgeneticsoncology.org/gene/55279/ilkap-(ilk-associated-serine-threonine-phosphatase)
