UBAP2L (ubiquitin associated protein 2 like)

2015-06-01  

Identity

HGNC
LOCATION
1q21.3
LOCUSID
ALIAS
NICE-4,NICE4
FUSION GENES

Other Information

Locus ID:

NCBI: 9898
MIM: 616472
HGNC: 29877
Ensembl: ENSG00000143569

Variants:

dbSNP: 9898
ClinVar: 9898
TCGA: ENSG00000143569
COSMIC: UBAP2L

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143569ENST00000271877F8W726
ENSG00000143569ENST00000343815Q14157
ENSG00000143569ENST00000361546Q14157
ENSG00000143569ENST00000368504Q5VU77
ENSG00000143569ENST00000412596Q5VU78
ENSG00000143569ENST00000428595H0Y5H6
ENSG00000143569ENST00000428931Q14157
ENSG00000143569ENST00000433615H7C2T8
ENSG00000143569ENST00000437652Q5VU79
ENSG00000143569ENST00000441890Q5VU81
ENSG00000143569ENST00000456325Q5VU80
ENSG00000143569ENST00000613315Q14157

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
289814792017Ubiquitin Associated Protein 2-Like (UBAP2L) Overexpression in Patients with Hepatocellular Carcinoma and its Clinical Significance.10
250696392014Knockdown of ubiquitin associated protein 2-like inhibits the growth and migration of prostate cancer cells.8
251852652014UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activity.8
291969132018UBAP2L silencing inhibits cell proliferation and G2/M phase transition in breast cancer.8
202009782010Replication of previous genome-wide association studies of bone mineral density in premenopausal American women.7
263102742015Downregulation of ubiquitin-associated protein 2-like with a short hairpin RNA inhibits human glioma cell growth in vitro.7
263817552016Arginine methylation of ubiquitin-associated protein 2-like is required for the accurate distribution of chromosomes.6
283347162017Downregulation of UBAP2L Inhibits the Epithelial-Mesenchymal Transition via SNAIL1 Regulation in Hepatocellular Carcinoma Cells.6
287547132017UBAP2L is amplified in a large subset of human lung adenocarcinoma and is critical for epithelial lung cell identity and tumor metastasis.4

Citation

Dessen P

UBAP2L (ubiquitin associated protein 2 like)

Atlas Genet Cytogenet Oncol Haematol. 2015-06-01

Online version: http://atlasgeneticsoncology.org/gene/55303/ubap2l-(ubiquitin-associated-protein-2-like)