Identity
HGNC
LOCATION
10q23.2
LOCUSID
ALIAS
FOE,KIAA0261,WAPAL
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23063
MIM: 610754
HGNC: 23293
Ensembl: ENSG00000062650
Variants:
dbSNP: 23063
ClinVar: 23063
TCGA: ENSG00000062650
COSMIC: WAPL
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000062650 | ENST00000263070 | Q8WVX6 |
| ENSG00000062650 | ENST00000298767 | Q7Z5K2 |
| ENSG00000062650 | ENST00000372075 | F6QZY1 |
| ENSG00000062650 | ENST00000618527 | Q7Z5K2 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35136067 | 2022 | A Mediator-cohesin axis controls heterochromatin domain formation. | 11 |
| 35136067 | 2022 | A Mediator-cohesin axis controls heterochromatin domain formation. | 11 |
| 33947962 | 2021 | WAPL induces cervical intraepithelial neoplasia modulated with estrogen signaling without HPV E6/E7. | 2 |
| 33947962 | 2021 | WAPL induces cervical intraepithelial neoplasia modulated with estrogen signaling without HPV E6/E7. | 2 |
| 32065581 | 2020 | ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesin(STAG1) from WAPL. | 62 |
| 32084359 | 2020 | WAPL-Dependent Repair of Damaged DNA Replication Forks Underlies Oncogene-Induced Loss of Sister Chromatid Cohesion. | 29 |
| 32065581 | 2020 | ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesin(STAG1) from WAPL. | 62 |
| 32084359 | 2020 | WAPL-Dependent Repair of Damaged DNA Replication Forks Underlies Oncogene-Induced Loss of Sister Chromatid Cohesion. | 29 |
| 30698808 | 2019 | Dysregulation of the cohesin subunit RAD21 by Hepatitis C virus mediates host-virus interactions. | 5 |
| 31204999 | 2019 | Absolute quantification of cohesin, CTCF and their regulators in human cells. | 43 |
| 31530811 | 2019 | Replication stress induces mitotic death through parallel pathways regulated by WAPL and telomere deprotection. | 26 |
| 30698808 | 2019 | Dysregulation of the cohesin subunit RAD21 by Hepatitis C virus mediates host-virus interactions. | 5 |
| 31204999 | 2019 | Absolute quantification of cohesin, CTCF and their regulators in human cells. | 43 |
| 31530811 | 2019 | Replication stress induces mitotic death through parallel pathways regulated by WAPL and telomere deprotection. | 26 |
| 29138236 | 2018 | A kinase-dependent role for Haspin in antagonizing Wapl and protecting mitotic centromere cohesion. | 26 |
Citation
Dessen P
WAPL (WAPL cohesin release factor)
Atlas Genet Cytogenet Oncol Haematol. 2015-08-01
Online version: http://atlasgeneticsoncology.org/gene/55307/wapl-(wapl-cohesin-release-factor)
