Identity
HGNC
LOCATION
20p12.3
LOCUSID
ALIAS
EDI3,GDE5,GDPD6,PREI4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 56261
MIM: 614124
HGNC: 26957
Ensembl: ENSG00000125772
Variants:
dbSNP: 56261
ClinVar: 56261
TCGA: ENSG00000125772
COSMIC: GPCPD1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000125772 | ENST00000379019 | Q9NPB8 |
| ENSG00000125772 | ENST00000418646 | H0Y565 |
| ENSG00000125772 | ENST00000481690 | A0A0J9YY12 |
| ENSG00000125772 | ENST00000633552 | A0A0J9YVP8 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38238601 | 2024 | Gpcpd1-GPC metabolic pathway is dysfunctional in aging and its deficiency severely perturbs glucose metabolism. | 0 |
| 38238601 | 2024 | Gpcpd1-GPC metabolic pathway is dysfunctional in aging and its deficiency severely perturbs glucose metabolism. | 0 |
| 36670508 | 2023 | Inhibiting the glycerophosphodiesterase EDI3 in ER-HER2+ breast cancer cells resistant to HER2-targeted therapy reduces viability and tumour growth. | 1 |
| 36803235 | 2023 | Hypoxia-induced GPCPD1 depalmitoylation triggers mitophagy via regulating PRKN-mediated ubiquitination of VDAC1. | 7 |
| 36670508 | 2023 | Inhibiting the glycerophosphodiesterase EDI3 in ER-HER2+ breast cancer cells resistant to HER2-targeted therapy reduces viability and tumour growth. | 1 |
| 36803235 | 2023 | Hypoxia-induced GPCPD1 depalmitoylation triggers mitophagy via regulating PRKN-mediated ubiquitination of VDAC1. | 7 |
| 34626691 | 2021 | Circular RNA circSNX6 promotes sunitinib resistance in renal cell carcinoma through the miR-1184/GPCPD1/ lysophosphatidic acid axis. | 17 |
| 34626691 | 2021 | Circular RNA circSNX6 promotes sunitinib resistance in renal cell carcinoma through the miR-1184/GPCPD1/ lysophosphatidic acid axis. | 17 |
| 25482527 | 2014 | EDI3 links choline metabolism to integrin expression, cell adhesion and spreading. | 21 |
| 25482527 | 2014 | EDI3 links choline metabolism to integrin expression, cell adhesion and spreading. | 21 |
| 22343285 | 2012 | Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. | 31 |
| 22570503 | 2012 | Choline-releasing glycerophosphodiesterase EDI3 drives tumor cell migration and metastasis. | 62 |
| 22343285 | 2012 | Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. | 31 |
| 22570503 | 2012 | Choline-releasing glycerophosphodiesterase EDI3 drives tumor cell migration and metastasis. | 62 |
Citation
Dessen P
GPCPD1 (glycerophosphocholine phosphodiesterase 1)
Atlas Genet Cytogenet Oncol Haematol. 2015-08-01
Online version: http://atlasgeneticsoncology.org/gene/55316/gpcpd1-(glycerophosphocholine-phosphodiesterase-1)
