Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 124976
MIM: 612584
HGNC: 26992
Ensembl: ENSG00000183018
Variants:
dbSNP: 124976
ClinVar: 124976
TCGA: ENSG00000183018
COSMIC: SPNS2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000183018 | ENST00000329078 | Q8IVW8 |
| ENSG00000183018 | ENST00000571386 | I3L4N9 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37728571 | 2024 | Spinster homolog 2 reduces malignancies of glioblastoma via PTEN/PI3K/AKT pathway. | 0 |
| 37728571 | 2024 | Spinster homolog 2 reduces malignancies of glioblastoma via PTEN/PI3K/AKT pathway. | 0 |
| 35614326 | 2023 | Iron Deficiency Increases Phosphorylation of SP1 to Upregulate SPNS2 Expression in Hepatocellular Carcinoma. | 3 |
| 37224812 | 2023 | Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate. | 7 |
| 37358015 | 2023 | Enhancing Spns2/S1P in macrophages alleviates hyperinflammation and prevents immunosuppression in sepsis. | 5 |
| 35614326 | 2023 | Iron Deficiency Increases Phosphorylation of SP1 to Upregulate SPNS2 Expression in Hepatocellular Carcinoma. | 3 |
| 37224812 | 2023 | Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate. | 7 |
| 37358015 | 2023 | Enhancing Spns2/S1P in macrophages alleviates hyperinflammation and prevents immunosuppression in sepsis. | 5 |
| 33673355 | 2021 | Prognostic Significance of Cytoplasmic SPNS2 Expression in Patients with Oral Squamous Cell Carcinoma. | 2 |
| 34671931 | 2021 | Long non-coding RNA HOXA-AS3 facilitates the malignancy in colorectal cancer by miR-4319/SPNS2 axis. | 4 |
| 33673355 | 2021 | Prognostic Significance of Cytoplasmic SPNS2 Expression in Patients with Oral Squamous Cell Carcinoma. | 2 |
| 34671931 | 2021 | Long non-coding RNA HOXA-AS3 facilitates the malignancy in colorectal cancer by miR-4319/SPNS2 axis. | 4 |
| 32253496 | 2020 | Mutation in ALOX12B likely cause of POI and also ichthyosis in a large Iranian pedigree. | 2 |
| 32253496 | 2020 | Mutation in ALOX12B likely cause of POI and also ichthyosis in a large Iranian pedigree. | 2 |
| 31206801 | 2019 | SPNS2 promotes the malignancy of colorectal cancer cells via regulating Akt and ERK pathway. | 14 |
Citation
Dessen P
SPNS2 (sphingolipid transporter 2)
Atlas Genet Cytogenet Oncol Haematol. 2015-08-01
Online version: http://atlasgeneticsoncology.org/gene/55322/spns2-(sphingolipid-transporter-2)
