HP1BP3 (heterochromatin protein 1 binding protein 3)

2015-08-01  

Identity

HGNC
LOCATION
1p36.12
LOCUSID
ALIAS
HP1-BP74,HP1BP74
FUSION GENES

Other Information

Locus ID:

NCBI: 50809
MIM: 616072
HGNC: 24973
Ensembl: ENSG00000127483

Variants:

dbSNP: 50809
ClinVar: 50809
TCGA: ENSG00000127483
COSMIC: HP1BP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000127483ENST00000312239Q5SSJ5
ENSG00000127483ENST00000375000Q5SSJ5
ENSG00000127483ENST00000375003Q5SSJ5
ENSG00000127483ENST00000414993B0QZK9
ENSG00000127483ENST00000417710B0QZK8
ENSG00000127483ENST00000419490B0QZK5
ENSG00000127483ENST00000419948B0QZK4
ENSG00000127483ENST00000424732Q5SWC8
ENSG00000127483ENST00000437575B0QZK6
ENSG00000127483ENST00000438032X6RGJ2
ENSG00000127483ENST00000443615B0QZK7

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
365175902023EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.3
365175902023EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.3
318191672020A fail-safe system to prevent oncogenesis by senescence is targeted by SV40 small T antigen.2
318191672020A fail-safe system to prevent oncogenesis by senescence is targeted by SV40 small T antigen.2
265033112016Replication of Epigenetic Postpartum Depression Biomarkers and Variation with Hormone Levels.34
274254092016HP1BP3, a Chromatin Retention Factor for Co-transcriptional MicroRNA Processing.17
265033112016Replication of Epigenetic Postpartum Depression Biomarkers and Variation with Hormone Levels.34
274254092016HP1BP3, a Chromatin Retention Factor for Co-transcriptional MicroRNA Processing.17
256626032015HP1BP3 is a novel histone H1 related protein with essential roles in viability and growth.16
264028432015Proportionate Dwarfism in Mice Lacking Heterochromatin Protein 1 Binding Protein 3 (HP1BP3) Is Associated With Alterations in the Endocrine IGF-1 Pathway.10
256626032015HP1BP3 is a novel histone H1 related protein with essential roles in viability and growth.16
264028432015Proportionate Dwarfism in Mice Lacking Heterochromatin Protein 1 Binding Protein 3 (HP1BP3) Is Associated With Alterations in the Endocrine IGF-1 Pathway.10
243173102014Seeing the future: epigenetic biomarkers of postpartum depression.6
248304162014Profiling of the Chromatin-associated Proteome Identifies HP1BP3 as a Novel Regulator of Cell Cycle Progression.24
251008602014Quantitative profiling of chromatome dynamics reveals a novel role for HP1BP3 in hypoxia-induced oncogenesis.21

Citation

Dessen P

HP1BP3 (heterochromatin protein 1 binding protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2015-08-01

Online version: http://atlasgeneticsoncology.org/gene/55344/hp1bp3-(heterochromatin-protein-1-binding-protein-3)