Identity
HGNC
LOCATION
16q22.1
LOCUSID
ALIAS
C16orf77,IL-34
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 146433
MIM: 612081
HGNC: 28529
Ensembl: ENSG00000157368
Variants:
dbSNP: 146433
ClinVar: 146433
TCGA: ENSG00000157368
COSMIC: IL34
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Cytokine Signaling in Immune system | REACTOME | R-HSA-1280215 |
| Signaling by Interleukins | REACTOME | R-HSA-449147 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38103407 | 2024 | Elevated serum IL-34 is correlated with disease severity in patients with biliary atresia following Kasai portoenterostomy. | 0 |
| 38166811 | 2024 | Cut-off value for interleukin-34 as an additional potential inflammatory biomarker for estimation of slow coronary flow risk. | 1 |
| 38218098 | 2024 | Longitudinal associations between serum IL-34 with severity and prognosis in community-acquired pneumonia patients. | 0 |
| 38367301 | 2024 | SAMHD1 dysfunction induces IL-34 expression via NF-κB p65 in neuronal SH-SY5Y cells. | 0 |
| 38103407 | 2024 | Elevated serum IL-34 is correlated with disease severity in patients with biliary atresia following Kasai portoenterostomy. | 0 |
| 38166811 | 2024 | Cut-off value for interleukin-34 as an additional potential inflammatory biomarker for estimation of slow coronary flow risk. | 1 |
| 38218098 | 2024 | Longitudinal associations between serum IL-34 with severity and prognosis in community-acquired pneumonia patients. | 0 |
| 38367301 | 2024 | SAMHD1 dysfunction induces IL-34 expression via NF-κB p65 in neuronal SH-SY5Y cells. | 0 |
| 34347576 | 2023 | Emerging roles of IL-34 in neurodegenerative and neurological infectious disease. | 0 |
| 36562687 | 2023 | Sp1 Controls the Basal Level of Interleukin-34 Transcription. | 0 |
| 37175932 | 2023 | BMP-2 Genome-Edited Human MSCs Protect against Cartilage Degeneration via Suppression of IL-34 in Collagen-Induced Arthritis. | 0 |
| 37533702 | 2023 | A mechanism of IL-34-induced resistance against cytotoxic anti-cancer therapies such as radiation by X-ray and chemotherapy by Oxaliplatin. | 1 |
| 37556943 | 2023 | Interleukin-34-NF-κB signaling aggravates myocardial ischemic/reperfusion injury by facilitating macrophage recruitment and polarization. | 2 |
| 37947892 | 2023 | Elevated circulating levels of IL-34 are strongly associated with osteoporosis. | 0 |
| 34347576 | 2023 | Emerging roles of IL-34 in neurodegenerative and neurological infectious disease. | 0 |
Citation
Dessen P
IL34 (interleukin 34)
Atlas Genet Cytogenet Oncol Haematol. 2015-08-01
Online version: http://atlasgeneticsoncology.org/gene/55352/il34-(interleukin-34)
