Identity
HGNC
LOCATION
13q22.3
LOCUSID
ALIAS
Myc-bp2,PAM,PHR1,Phr
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23077
MIM: 610392
HGNC: 23386
Ensembl: ENSG00000005810
Variants:
dbSNP: 23077
ClinVar: 23077
TCGA: ENSG00000005810
COSMIC: MYCBP2
RNA/Proteins
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38289221 | 2024 | Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function. | 1 |
| 38289221 | 2024 | Ubiquitin ligase and signalling hub MYCBP2 is required for efficient EPHB2 tyrosine kinase receptor function. | 1 |
| 36200388 | 2023 | Loss-of-function variants in MYCBP2 cause neurobehavioural phenotypes and corpus callosum defects. | 10 |
| 36200388 | 2023 | Loss-of-function variants in MYCBP2 cause neurobehavioural phenotypes and corpus callosum defects. | 10 |
| 36582246 | 2022 | MYCBP2 expression correlated with inflammatory cell infiltration and prognosis immunotherapy in thyroid cancer patients. | 2 |
| 36582246 | 2022 | MYCBP2 expression correlated with inflammatory cell infiltration and prognosis immunotherapy in thyroid cancer patients. | 2 |
| 31285543 | 2020 | FBXO45-MYCBP2 regulates mitotic cell fate by targeting FBXW7 for degradation. | 20 |
| 31285543 | 2020 | FBXO45-MYCBP2 regulates mitotic cell fate by targeting FBXW7 for degradation. | 20 |
| 29643511 | 2018 | Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity. | 105 |
| 30318507 | 2018 | Epigenetically regulated miR-1247 functions as a novel tumour suppressor via MYCBP2 in methylator colon cancers. | 10 |
| 29643511 | 2018 | Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity. | 105 |
| 30318507 | 2018 | Epigenetically regulated miR-1247 functions as a novel tumour suppressor via MYCBP2 in methylator colon cancers. | 10 |
| 25460509 | 2015 | Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors. | 51 |
| 25634536 | 2015 | High myopia-excavated optic disc anomaly associated with a frameshift mutation in the MYC-binding protein 2 gene (MYCBP2). | 9 |
| 25731699 | 2015 | MiR-1247-5p is overexpressed in castration resistant prostate cancer and targets MYCBP2. | 26 |
Citation
Dessen P
MYCBP2 (MYC binding protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2015-08-01
Online version: http://atlasgeneticsoncology.org/gene/55356/mycbp2-(myc-binding-protein-2)
