GPR137 (G protein-coupled receptor 137)

2015-08-01 Affiliation

Identity

HGNC

GPR137

LOCATION

11q13.1

LOCUSID

56834

ALIAS

C11orf4,GPR137A,TM7SF1L1

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 56834
HGNC: 24300
Ensembl: ENSG00000173264

Variants:

dbSNP: 56834
ClinVar: 56834
TCGA: ENSG00000173264
COSMIC: GPR137

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000173264	ENST00000313074	Q96N19
ENSG00000173264	ENST00000377702	Q96N19
ENSG00000173264	ENST00000411458	Q96N19
ENSG00000173264	ENST00000438980	Q96N19
ENSG00000173264	ENST00000535675	F5H1V9
ENSG00000173264	ENST00000536282	H0YGJ1
ENSG00000173264	ENST00000536667	F5GXW8
ENSG00000173264	ENST00000538032	F5H4R8
ENSG00000173264	ENST00000538244	F5H7S0
ENSG00000173264	ENST00000539833	F5H0Q1
ENSG00000173264	ENST00000539851	Q96N19
ENSG00000173264	ENST00000540370	F5H1T3
ENSG00000173264	ENST00000541952	F5H6Y8
ENSG00000173264	ENST00000542190	F5GXD9
ENSG00000173264	ENST00000543383	F5GXI8
ENSG00000173264	ENST00000546139	F5H234
ENSG00000173264	ENST00000546201	F5H097

Expression (GTEx)

100

150

200

250

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
25471990	2015	Knockdown of GPR137 by RNAi inhibits pancreatic cancer cell growth and induces apoptosis.	6
24870220	2014	Inhibition of GPR137 expression reduces the proliferation and colony formation of malignant glioma cells.	4
25524330	2015	Inhibition of GPR137 suppresses proliferation of medulloblastoma cells in vitro.	4
26669804	2016	Knockdown of GPR137,G Protein-coupled receptor 137, Inhibits the Proliferation and Migration of Human Prostate Cancer Cells.	4
25490967	2015	Down-regulation of G protein-coupled receptor 137 by RNA interference inhibits cell growth of two hepatoma cell lines.	3
25496438	2015	G-protein-coupled receptor 137 accelerates proliferation of urinary bladder cancer cells in vitro.	3
28975893	2017	The ESRP1-GPR137 axis contributes to intestinal pathogenesis.	3
29739299	2018	GRP137 promotes cell proliferation and metastasis through regulation of the PI3K/AKT pathway in human ovarian cancer.	2
31464892	2019	GPR137 is a promising novel bio-marker for the prognosis of bladder cancer patients.	0

Citation

Dessen P

GPR137 (G protein-coupled receptor 137)

Atlas Genet Cytogenet Oncol Haematol. 2015-08-01

Online version: http://atlasgeneticsoncology.org/gene/55360/gpr137-(g-protein-coupled-receptor-137)