Identity
HGNC
LOCATION
7q33
LOCUSID
ALIAS
CLONE243,NOT4,NOT4H
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4850
MIM: 604911
HGNC: 7880
Ensembl: ENSG00000080802
Variants:
dbSNP: 4850
ClinVar: 4850
TCGA: ENSG00000080802
COSMIC: CNOT4
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37493105 | 2023 | CNOT4 suppresses nonsmall cell lung cancer progression by promoting the degradation of PAF1. | 2 |
| 37493105 | 2023 | CNOT4 suppresses nonsmall cell lung cancer progression by promoting the degradation of PAF1. | 2 |
| 33451139 | 2021 | The Interplay between HGF/c-met Axis and Nox4 in BRAF Mutated Melanoma. | 3 |
| 33592572 | 2021 | CNOT4 suppresses non-small cell lung cancer progression and is required for effector cytolytic T lymphocytes cell responses to lung cancer cells. | 1 |
| 34626022 | 2021 | Aberrant expression of MYD88 via RNA-controlling CNOT4 and EXOSC3 in colonic mucosa impacts generation of colonic cancer. | 3 |
| 33451139 | 2021 | The Interplay between HGF/c-met Axis and Nox4 in BRAF Mutated Melanoma. | 3 |
| 33592572 | 2021 | CNOT4 suppresses non-small cell lung cancer progression and is required for effector cytolytic T lymphocytes cell responses to lung cancer cells. | 1 |
| 34626022 | 2021 | Aberrant expression of MYD88 via RNA-controlling CNOT4 and EXOSC3 in colonic mucosa impacts generation of colonic cancer. | 3 |
| 33034149 | 2020 | CNOT4 enhances the efficacy of anti-PD-1 immunotherapy in a model of non-small cell lung cancer. | 1 |
| 33034149 | 2020 | CNOT4 enhances the efficacy of anti-PD-1 immunotherapy in a model of non-small cell lung cancer. | 1 |
| 30692204 | 2019 | A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4-NOT complex. | 25 |
| 30692204 | 2019 | A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4-NOT complex. | 25 |
| 29802328 | 2018 | The conserved RNA recognition motif and C3H1 domain of the Not4 ubiquitin ligase regulate in vivo ligase function. | 9 |
| 29861391 | 2018 | Ubiquitination of ABCE1 by NOT4 in Response to Mitochondrial Damage Links Co-translational Quality Control to PINK1-Directed Mitophagy. | 29 |
| 29802328 | 2018 | The conserved RNA recognition motif and C3H1 domain of the Not4 ubiquitin ligase regulate in vivo ligase function. | 9 |
Citation
Dessen P
CNOT4 (CCR4-NOT transcription complex subunit 4)
Atlas Genet Cytogenet Oncol Haematol. 2015-08-01
Online version: http://atlasgeneticsoncology.org/gene/55380/cnot4-(ccr4-not-transcription-complex-subunit-4)
