IGSF1 (immunoglobulin superfamily member 1)

2015-08-01  

Identity

HGNC
LOCATION
Xq26.1
LOCUSID
ALIAS
CHTE,IGCD1,IGDC1,INHBP,PGSF2,p120
FUSION GENES

Other Information

Locus ID:

NCBI: 3547
MIM: 300137
HGNC: 5948
Ensembl: ENSG00000147255

Variants:

dbSNP: 3547
ClinVar: 3547
TCGA: ENSG00000147255
COSMIC: IGSF1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000147255ENST00000361420Q8N6C5
ENSG00000147255ENST00000370900Q8N6C5
ENSG00000147255ENST00000370901Q8N6C5
ENSG00000147255ENST00000370903Q8N6C5
ENSG00000147255ENST00000370904Q8N6C5
ENSG00000147255ENST00000370910Q8N6C5
ENSG00000147255ENST00000650730A0A494C0E7
ENSG00000147255ENST00000650945A0A494C0H8
ENSG00000147255ENST00000651402A0A494C0W8
ENSG00000147255ENST00000651556Q8N6C5
ENSG00000147255ENST00000652189A0A494C0K8

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
368544082023[Clinical characteristics and genetic analysis of four patients with central hypothyroidism due to IGSF1 gene variants].0
368544082023[Clinical characteristics and genetic analysis of four patients with central hypothyroidism due to IGSF1 gene variants].0
353500162022Congenital Central Hypothyroidism Caused by a Novel IGSF1 Variant Identified in a French Family.1
354564292022Case Report: A Detailed Phenotypic Description of Patients and Relatives with Combined Central Hypothyroidism and Growth Hormone Deficiency Carrying IGSF1 Mutations.1
362011632022IGSF1 mutations are the most frequent genetic aetiology of thyrotropin deficiency.0
364646002022IGSF1 mutation as a cause of isolated central hypothyroidism.0
353500162022Congenital Central Hypothyroidism Caused by a Novel IGSF1 Variant Identified in a French Family.1
354564292022Case Report: A Detailed Phenotypic Description of Patients and Relatives with Combined Central Hypothyroidism and Growth Hormone Deficiency Carrying IGSF1 Mutations.1
362011632022IGSF1 mutations are the most frequent genetic aetiology of thyrotropin deficiency.0
364646002022IGSF1 mutation as a cause of isolated central hypothyroidism.0
316501572020IGSF1 Deficiency Results in Human and Murine Somatotrope Neurosecretory Hyperfunction.16
316501572020IGSF1 Deficiency Results in Human and Murine Somatotrope Neurosecretory Hyperfunction.16
315046372019Genetics of Congenital Isolated TSH Deficiency: Mutation Screening of the Known Causative Genes and a Literature Review.9
315046372019Genetics of Congenital Isolated TSH Deficiency: Mutation Screening of the Known Causative Genes and a Literature Review.9
263874892016Mild deficits in attentional control in patients with the IGSF1 deficiency syndrome.9

Citation

Dessen P

IGSF1 (immunoglobulin superfamily member 1)

Atlas Genet Cytogenet Oncol Haematol. 2015-08-01

Online version: http://atlasgeneticsoncology.org/gene/55381/igsf1-(immunoglobulin-superfamily-member-1)