CLIC3 (chloride intracellular channel 3)

2015-08-01  

Identity

HGNC
LOCATION
9q34.3
LOCUSID
ALIAS
-

Other Information

Locus ID:

NCBI: 9022
MIM: 606533
HGNC: 2064
Ensembl: ENSG00000169583

Variants:

dbSNP: 9022
ClinVar: 9022
TCGA: ENSG00000169583
COSMIC: CLIC3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000169583ENST00000494426O95833

Expression (GTEx)

0
50
100
150
200
250
300
350
400

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
250152902014CLIC3 controls recycling of late endosomal MT1-MMP and dictates invasion and metastasis in breast cancer.41
281983602017Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity.19
201463632010Structure of human CLIC3 at 2 A resolution.11
264453682015Transcriptional over-expression of chloride intracellular channels 3 and 4 in malignant pleural mesothelioma.10
170270782007Expression and cellular localisation of chloride intracellular channel 3 in human placenta and fetal membranes.9
227955782012Placental CLIC3 is increased in fetal growth restriction and pre-eclampsia affected human pregnancies.6

Citation

Dessen P

CLIC3 (chloride intracellular channel 3)

Atlas Genet Cytogenet Oncol Haematol. 2015-08-01

Online version: http://atlasgeneticsoncology.org/gene/55383/clic3-(chloride-intracellular-channel-3)