Identity
HGNC
LOCATION
11q21
LOCUSID
ALIAS
CRSP6,CRSP77,DRIP80,SRB4,TRAP80
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9440
MIM: 603810
HGNC: 2375
Ensembl: ENSG00000042429
Variants:
dbSNP: 9440
ClinVar: 9440
TCGA: ENSG00000042429
COSMIC: MED17
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36508181 | 2022 | An expansion of phenotype: novel homozygous variant in the MED17 identified in patients with progressive microcephaly and global developmental delay. | 0 |
| 36508181 | 2022 | An expansion of phenotype: novel homozygous variant in the MED17 identified in patients with progressive microcephaly and global developmental delay. | 0 |
| 33596087 | 2021 | The cell polarity kinase Par1b/MARK2 activation selects specific NF-kB transcripts via phosphorylation of core mediator Med17/TRAP80. | 2 |
| 33756211 | 2021 | Delineation of the phenotype of MED17-related disease in Caucasus-Jewish families. | 0 |
| 34392449 | 2021 | Increased unfolded protein responses caused by MED17 mutations. | 2 |
| 33596087 | 2021 | The cell polarity kinase Par1b/MARK2 activation selects specific NF-kB transcripts via phosphorylation of core mediator Med17/TRAP80. | 2 |
| 33756211 | 2021 | Delineation of the phenotype of MED17-related disease in Caucasus-Jewish families. | 0 |
| 34392449 | 2021 | Increased unfolded protein responses caused by MED17 mutations. | 2 |
| 25437875 | 2015 | Hepatic TRAP80 selectively regulates lipogenic activity of liver X receptor. | 15 |
| 25482373 | 2015 | Human mediator MED17 subunit plays essential roles in gene regulation by associating with the transcription and DNA repair machineries. | 7 |
| 25437875 | 2015 | Hepatic TRAP80 selectively regulates lipogenic activity of liver X receptor. | 15 |
| 25482373 | 2015 | Human mediator MED17 subunit plays essential roles in gene regulation by associating with the transcription and DNA repair machineries. | 7 |
| 21326907 | 2011 | Mediator and post-recruitment regulation of RNA polymerase II. | 17 |
| 21326907 | 2011 | Mediator and post-recruitment regulation of RNA polymerase II. | 17 |
| 20950787 | 2010 | Infantile cerebral and cerebellar atrophy is associated with a mutation in the MED17 subunit of the transcription preinitiation mediator complex. | 28 |
Citation
Dessen P
MED17 (mediator complex subunit 17)
Atlas Genet Cytogenet Oncol Haematol. 2015-10-01
Online version: http://atlasgeneticsoncology.org/gene/55422/med17-(mediator-complex-subunit-17)
