PHF21B (PHD finger protein 21B)

2015-10-01  

Identity

HGNC
PHF21B
LOCATION
22q13.31
LOCUSID
112885
ALIAS
BHC80L,PHF4
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 112885
MIM: 616727
HGNC: 25161
Ensembl: ENSG00000056487

Variants:

dbSNP: 112885
ClinVar: 112885
TCGA: ENSG00000056487
COSMIC: PHF21B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000056487ENST00000313237Q96EK2
ENSG00000056487ENST00000313237A0A0S2Z6R3
ENSG00000056487ENST00000396103Q96EK2
ENSG00000056487ENST00000403565B1AHC5
ENSG00000056487ENST00000414269B1AHC6
ENSG00000056487ENST00000420689B0QYW2
ENSG00000056487ENST00000629843Q96EK2
ENSG00000056487ENST00000629843A0A0S2Z665

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
277774182017The PHF21B gene is associated with major depression and modulates the stress response.27
286453122017PHF21B overexpression promotes cancer stem cell-like traits in prostate cancer cells by activating the Wnt/β-catenin signaling pathway.15
277774182017The PHF21B gene is associated with major depression and modulates the stress response.27
286453122017PHF21B overexpression promotes cancer stem cell-like traits in prostate cancer cells by activating the Wnt/β-catenin signaling pathway.15
254548212015PHF21B as a candidate tumor suppressor gene in head and neck squamous cell carcinomas.14
254548212015PHF21B as a candidate tumor suppressor gene in head and neck squamous cell carcinomas.14
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

PHF21B (PHD finger protein 21B)

Atlas Genet Cytogenet Oncol Haematol. 2015-10-01

Online version: http://atlasgeneticsoncology.org/gene/55425/phf21b-(phd-finger-protein-21b)