Identity
HGNC
LOCATION
10q21.3
LOCUSID
ALIAS
COPR,COPR1,COPR2,NRBF-2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 29982
MIM: 616477
HGNC: 19692
Ensembl: ENSG00000148572
Variants:
dbSNP: 29982
ClinVar: 29982
TCGA: ENSG00000148572
COSMIC: NRBF2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000148572 | ENST00000277746 | Q96F24 |
| ENSG00000148572 | ENST00000435510 | Q96F24 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36333468 | 2022 | NRBF2-mediated autophagy contributes to metabolite replenishment and radioresistance in glioblastoma. | 2 |
| 36333468 | 2022 | NRBF2-mediated autophagy contributes to metabolite replenishment and radioresistance in glioblastoma. | 2 |
| 32160108 | 2021 | PI3KC3 complex subunit NRBF2 is required for apoptotic cell clearance to restrict intestinal inflammation. | 32 |
| 32160108 | 2021 | PI3KC3 complex subunit NRBF2 is required for apoptotic cell clearance to restrict intestinal inflammation. | 32 |
| 31775806 | 2019 | Autophagy protein NRBF2 has reduced expression in Alzheimer's brains and modulates memory and amyloid-beta homeostasis in mice. | 33 |
| 31775806 | 2019 | Autophagy protein NRBF2 has reduced expression in Alzheimer's brains and modulates memory and amyloid-beta homeostasis in mice. | 33 |
| 28059666 | 2017 | MTORC1-mediated NRBF2 phosphorylation functions as a switch for the class III PtdIns3K and autophagy. | 46 |
| 28980867 | 2017 | NRBF2 is involved in the autophagic degradation process of APP-CTFs in Alzheimer disease models. | 46 |
| 28059666 | 2017 | MTORC1-mediated NRBF2 phosphorylation functions as a switch for the class III PtdIns3K and autophagy. | 46 |
| 28980867 | 2017 | NRBF2 is involved in the autophagic degradation process of APP-CTFs in Alzheimer disease models. | 46 |
| 27385829 | 2016 | Dynamics and architecture of the NRBF2-containing phosphatidylinositol 3-kinase complex I of autophagy. | 46 |
| 27630019 | 2016 | Characterization of Atg38 and NRBF2, a fifth subunit of the autophagic Vps34/PIK3C3 complex. | 35 |
| 27385829 | 2016 | Dynamics and architecture of the NRBF2-containing phosphatidylinositol 3-kinase complex I of autophagy. | 46 |
| 27630019 | 2016 | Characterization of Atg38 and NRBF2, a fifth subunit of the autophagic Vps34/PIK3C3 complex. | 35 |
| 26073781 | 2015 | Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression. | 25 |
Citation
Dessen P
NRBF2 (nuclear receptor binding factor 2)
Atlas Genet Cytogenet Oncol Haematol. 2015-10-01
Online version: http://atlasgeneticsoncology.org/gene/55441/nrbf2-(nuclear-receptor-binding-factor-2)
