Identity
HGNC
LOCATION
11q12.1
LOCUSID
ALIAS
DMS-8,DSM-8,DSM8,FKSG11,PZF,ZFP-91,ZNF757
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 80829
HGNC: 14983
Ensembl: ENSG00000186660
Variants:
dbSNP: 80829
ClinVar: 80829
TCGA: ENSG00000186660
COSMIC: ZFP91
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000186660 | ENST00000316059 | Q96JP5 |
| ENSG00000186660 | ENST00000316059 | A0A024R4Z1 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34936696 | 2022 | Overcoming IMiD resistance in T-cell lymphomas through potent degradation of ZFP91 and IKZF1. | 8 |
| 34942311 | 2022 | Zinc finger protein 91 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation. | 4 |
| 36375317 | 2022 | Atypical E3 ligase ZFP91 promotes small-molecule-induced E2F2 transcription factor degradation for cancer therapy. | 9 |
| 34936696 | 2022 | Overcoming IMiD resistance in T-cell lymphomas through potent degradation of ZFP91 and IKZF1. | 8 |
| 34942311 | 2022 | Zinc finger protein 91 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation. | 4 |
| 36375317 | 2022 | Atypical E3 ligase ZFP91 promotes small-molecule-induced E2F2 transcription factor degradation for cancer therapy. | 9 |
| 33755268 | 2021 | Zinc finger protein 91 accelerates tumour progression by activating β-catenin signalling in pancreatic cancer. | 6 |
| 34403361 | 2021 | ZFP91 disturbs metabolic fitness and antitumor activity of tumor-infiltrating T cells. | 9 |
| 33755268 | 2021 | Zinc finger protein 91 accelerates tumour progression by activating β-catenin signalling in pancreatic cancer. | 6 |
| 34403361 | 2021 | ZFP91 disturbs metabolic fitness and antitumor activity of tumor-infiltrating T cells. | 9 |
| 31046116 | 2020 | The ubiquitinase ZFP91 promotes tumor cell survival and confers chemoresistance through FOXA1 destabilization. | 13 |
| 32630670 | 2020 | Roles of miR-640 and Zinc Finger Protein 91 (ZFP91) in Angiopoietin-1-Induced In Vitro Angiogenesis. | 8 |
| 32754263 | 2020 | E3 ligase ZFP91 inhibits Hepatocellular Carcinoma Metabolism Reprogramming by regulating PKM splicing. | 30 |
| 32945499 | 2020 | MicroRNA‑188‑5p inhibits the progression of breast cancer by targeting zinc finger protein 91. | 4 |
| 31046116 | 2020 | The ubiquitinase ZFP91 promotes tumor cell survival and confers chemoresistance through FOXA1 destabilization. | 13 |
Citation
Dessen P
ZFP91 (ZFP91 zinc finger protein, atypical E3 ubiquitin ligase)
Atlas Genet Cytogenet Oncol Haematol. 2015-10-01
Online version: http://atlasgeneticsoncology.org/gene/55499/zfp91-(zfp91-zinc-finger-protein-atypical-e3-ubiquitin-ligase)
