Identity
HGNC
LOCATION
11p14.1
LOCUSID
ALIAS
LIN-7-C,LIN-7C,MALS-3,MALS3,VELI3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55327
MIM: 612332
HGNC: 17789
Ensembl: ENSG00000148943
Variants:
dbSNP: 55327
ClinVar: 55327
TCGA: ENSG00000148943
COSMIC: LIN7C
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000148943 | ENST00000278193 | Q9NUP9 |
| ENSG00000148943 | ENST00000524596 | G3V1D4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 24961284 | 2014 | Suppression of metastasis by mirtazapine via restoration of the Lin-7C/β-catenin pathway in human cancer cells. | 5 |
| 24961284 | 2014 | Suppression of metastasis by mirtazapine via restoration of the Lin-7C/β-catenin pathway in human cancer cells. | 5 |
| 20215397 | 2010 | Implication of genetic variants near NEGR1, SEC16B, TMEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, and KCTD15 with obesity and type 2 diabetes in 7705 Chinese. | 58 |
| 20702775 | 2010 | Structural basis for tandem L27 domain-mediated polymerization. | 8 |
| 20215397 | 2010 | Implication of genetic variants near NEGR1, SEC16B, TMEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, and KCTD15 with obesity and type 2 diabetes in 7705 Chinese. | 58 |
| 20702775 | 2010 | Structural basis for tandem L27 domain-mediated polymerization. | 8 |
| 18286632 | 2008 | Association study of brain-derived neurotrophic factor (BDNF) and LIN-7 homolog (LIN-7) genes with adult attention-deficit/hyperactivity disorder. | 16 |
| 18286632 | 2008 | Association study of brain-derived neurotrophic factor (BDNF) and LIN-7 homolog (LIN-7) genes with adult attention-deficit/hyperactivity disorder. | 16 |
| 18543122 | 2008 | Association study of theta EEG asymmetry and brain-derived neurotrophic factor gene variants in childhood-onset mood disorder. | 5 |
| 18286632 | 2008 | Association study of brain-derived neurotrophic factor (BDNF) and LIN-7 homolog (LIN-7) genes with adult attention-deficit/hyperactivity disorder. | 16 |
| 18286632 | 2008 | Association study of brain-derived neurotrophic factor (BDNF) and LIN-7 homolog (LIN-7) genes with adult attention-deficit/hyperactivity disorder. | 16 |
| 18543122 | 2008 | Association study of theta EEG asymmetry and brain-derived neurotrophic factor gene variants in childhood-onset mood disorder. | 5 |
| 17237226 | 2007 | The stardust family protein MPP7 forms a tripartite complex with LIN7 and DLG1 that regulates the stability and localization of DLG1 to cell junctions. | 37 |
| 17942893 | 2007 | Lin-7C/VELI3/MALS-3: an essential component in metastasis of human squamous cell carcinoma. | 9 |
| 17237226 | 2007 | The stardust family protein MPP7 forms a tripartite complex with LIN7 and DLG1 that regulates the stability and localization of DLG1 to cell junctions. | 37 |
Citation
Dessen P
LIN7C (lin-7 homolog C, crumbs cell polarity complex component)
Atlas Genet Cytogenet Oncol Haematol. 2015-11-01
Online version: http://atlasgeneticsoncology.org/gene/55505/lin7c-(lin-7-homolog-c-crumbs-cell-polarity-complex-component)
