Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3263
MIM: 142290
HGNC: 5171
Ensembl: ENSG00000110169
Variants:
dbSNP: 3263
ClinVar: 3263
TCGA: ENSG00000110169
COSMIC: HPX
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000110169 | ENST00000265983 | P02790 |
| ENSG00000110169 | ENST00000615166 | Q9BS19 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Vesicle-mediated transport | REACTOME | R-HSA-5653656 |
| Binding and Uptake of Ligands by Scavenger Receptors | REACTOME | R-HSA-2173782 |
| Scavenging of heme from plasma | REACTOME | R-HSA-2168880 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37899696 | 2023 | Free heme and hemopexin in acute kidney injury after cardiopulmonary bypass and transient renal ischemia. | 1 |
| 37899696 | 2023 | Free heme and hemopexin in acute kidney injury after cardiopulmonary bypass and transient renal ischemia. | 1 |
| 34564750 | 2022 | Evaluation of the relationship between intravascular hemolysis and clinical manifestations in sickle cell disease: decreased hemopexin during vaso-occlusive crises and increased inflammation in acute chest syndrome. | 4 |
| 35470713 | 2022 | Heme oxygenase-1 and hemopexin gene polymorphisms and the risk of anti-tuberculosis drug-induced hepatotoxicity in China. | 1 |
| 34564750 | 2022 | Evaluation of the relationship between intravascular hemolysis and clinical manifestations in sickle cell disease: decreased hemopexin during vaso-occlusive crises and increased inflammation in acute chest syndrome. | 4 |
| 35470713 | 2022 | Heme oxygenase-1 and hemopexin gene polymorphisms and the risk of anti-tuberculosis drug-induced hepatotoxicity in China. | 1 |
| 33813281 | 2021 | Widespread severe cerebral elevations of haptoglobin and haemopexin in sporadic Alzheimer's disease: Evidence for a pervasive microvasculopathy. | 4 |
| 33813281 | 2021 | Widespread severe cerebral elevations of haptoglobin and haemopexin in sporadic Alzheimer's disease: Evidence for a pervasive microvasculopathy. | 4 |
| 32915914 | 2020 | Hemopexin and α1-microglobulin heme scavengers with differential involvement in preeclampsia and fetal growth restriction. | 6 |
| 32966797 | 2020 | Scavenging of Labile Heme by Hemopexin Is a Key Checkpoint in Cancer Growth and Metastases. | 21 |
| 32915914 | 2020 | Hemopexin and α1-microglobulin heme scavengers with differential involvement in preeclampsia and fetal growth restriction. | 6 |
| 32966797 | 2020 | Scavenging of Labile Heme by Hemopexin Is a Key Checkpoint in Cancer Growth and Metastases. | 21 |
| 30226858 | 2018 | Novel urinary exosomal biomarkers of acute T cell-mediated rejection in kidney transplant recipients: A cross-sectional study. | 38 |
| 30226858 | 2018 | Novel urinary exosomal biomarkers of acute T cell-mediated rejection in kidney transplant recipients: A cross-sectional study. | 38 |
| 28596380 | 2017 | Identification of oxidative modifications of hemopexin and their predicted physiological relevance. | 9 |
Citation
Dessen P
HPX (hemopexin)
Atlas Genet Cytogenet Oncol Haematol. 2015-11-01
Online version: http://atlasgeneticsoncology.org/gene/55516/hpx-(hemopexin)
