Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5355
MIM: 300112
HGNC: 9087
Ensembl: ENSG00000102007
Variants:
dbSNP: 5355
ClinVar: 5355
TCGA: ENSG00000102007
COSMIC: PLP2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000102007 | ENST00000376322 | Q04941 |
| ENSG00000102007 | ENST00000376327 | Q04941 |
| ENSG00000102007 | ENST00000376327 | A0A024QYW3 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36921056 | 2023 | Structural basis of plp2-mediated cytoskeletal protein folding by TRiC/CCT. | 5 |
| 37715423 | 2023 | Low Expression of A3C and PLP2 Indicating a Favorable Prognosis in Human Gliomas. | 0 |
| 38085372 | 2023 | Reduced Proteolipid Protein 2 promotes endoplasmic reticulum stress-related apoptosis and increases drug sensitivity in acute myeloid leukemia. | 0 |
| 36921056 | 2023 | Structural basis of plp2-mediated cytoskeletal protein folding by TRiC/CCT. | 5 |
| 37715423 | 2023 | Low Expression of A3C and PLP2 Indicating a Favorable Prognosis in Human Gliomas. | 0 |
| 38085372 | 2023 | Reduced Proteolipid Protein 2 promotes endoplasmic reticulum stress-related apoptosis and increases drug sensitivity in acute myeloid leukemia. | 0 |
| 35190586 | 2022 | PLP2-derived peptide Rb4 triggers PARP-1-mediated necrotic death in murine melanoma cells. | 3 |
| 35190586 | 2022 | PLP2-derived peptide Rb4 triggers PARP-1-mediated necrotic death in murine melanoma cells. | 3 |
| 33859750 | 2021 | CD45RO(-)CD8(+) T cell-derived exosomes restrict estrogen-driven endometrial cancer development via the ERβ/miR-765/PLP2/Notch axis. | 32 |
| 34409455 | 2021 | PLP2 drives collective cell migration via ZO-1-mediated cytoskeletal remodeling at the leading edge in human colorectal cancer cells. | 4 |
| 33859750 | 2021 | CD45RO(-)CD8(+) T cell-derived exosomes restrict estrogen-driven endometrial cancer development via the ERβ/miR-765/PLP2/Notch axis. | 32 |
| 34409455 | 2021 | PLP2 drives collective cell migration via ZO-1-mediated cytoskeletal remodeling at the leading edge in human colorectal cancer cells. | 4 |
| 31778016 | 2020 | Reduced expression of proteolipid protein 2 increases ER stress-induced apoptosis and autophagy in glioblastoma. | 5 |
| 31901870 | 2020 | MiR-765 functions as a tumour suppressor and eliminates lipids in clear cell renal cell carcinoma by downregulating PLP2. | 32 |
| 32596309 | 2020 | PLP2 Expression as a Prognostic and Therapeutic Indicator in High-Risk Multiple Myeloma. | 3 |
Citation
Dessen P
PLP2 (proteolipid protein 2)
Atlas Genet Cytogenet Oncol Haematol. 2015-11-01
Online version: http://atlasgeneticsoncology.org/gene/55524/plp2-(proteolipid-protein-2)
