Identity
HGNC
LOCATION
17p13.2
LOCUSID
ALIAS
LTXS1,SATX2,SAX2,SPAX2,SPG58
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10749
MIM: 603060
HGNC: 6317
Ensembl: ENSG00000129250
Variants:
dbSNP: 10749
ClinVar: 10749
TCGA: ENSG00000129250
COSMIC: KIF1C
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000129250 | ENST00000320785 | O43896 |
| ENSG00000129250 | ENST00000574165 | I3L1B1 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38726004 | 2024 | KIF1C and new Huntingtin-interacting protein 1 binding proteins regulate rheumatoid arthritis fibroblast-like synoviocytes' phenotypes. | 0 |
| 38726004 | 2024 | KIF1C and new Huntingtin-interacting protein 1 binding proteins regulate rheumatoid arthritis fibroblast-like synoviocytes' phenotypes. | 0 |
| 35654143 | 2022 | c-Src-mediated phosphorylation and activation of kinesin KIF1C promotes elongation of invadopodia in cancer cells. | 3 |
| 35961316 | 2022 | Force generation of KIF1C is impaired by pathogenic mutations. | 2 |
| 36099894 | 2022 | Intracellular transport: KIF1C produces force along with a few slips. | 1 |
| 35654143 | 2022 | c-Src-mediated phosphorylation and activation of kinesin KIF1C promotes elongation of invadopodia in cancer cells. | 3 |
| 35961316 | 2022 | Force generation of KIF1C is impaired by pathogenic mutations. | 2 |
| 36099894 | 2022 | Intracellular transport: KIF1C produces force along with a few slips. | 1 |
| 31217419 | 2019 | PTPN21 and Hook3 relieve KIF1C autoinhibition and activate intracellular transport. | 34 |
| 31413903 | 2019 | KIF1C Variants Are Associated with Hypomyelination, Ataxia, Tremor, and Dystonia in Fraternal Twins. | 4 |
| 31217419 | 2019 | PTPN21 and Hook3 relieve KIF1C autoinhibition and activate intracellular transport. | 34 |
| 31413903 | 2019 | KIF1C Variants Are Associated with Hypomyelination, Ataxia, Tremor, and Dystonia in Fraternal Twins. | 4 |
| 29544888 | 2018 | Clinical phenotype of hereditary spastic paraplegia due to KIF1C gene mutations across life span. | 7 |
| 29544888 | 2018 | Clinical phenotype of hereditary spastic paraplegia due to KIF1C gene mutations across life span. | 7 |
| 29123223 | 2017 | Structural basis of small molecule ATPase inhibition of a human mitotic kinesin motor protein. | 8 |
Citation
Dessen P
KIF1C (kinesin family member 1C)
Atlas Genet Cytogenet Oncol Haematol. 2015-11-01
Online version: http://atlasgeneticsoncology.org/gene/55537/kif1c-(kinesin-family-member-1c)
