Identity
HGNC
LOCATION
14q23.2
LOCUSID
ALIAS
SPP-1,SPPase1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 81537
MIM: 612826
HGNC: 17720
Ensembl: ENSG00000126821
Variants:
dbSNP: 81537
ClinVar: 81537
TCGA: ENSG00000126821
COSMIC: SGPP1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000126821 | ENST00000247225 | Q9BX95 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35081855 | 2022 | MicroRNA-656-3p inhibits colorectal cancer cell migration, invasion, and chemo-resistance by targeting sphingosine-1-phosphate phosphatase 1. | 4 |
| 35081855 | 2022 | MicroRNA-656-3p inhibits colorectal cancer cell migration, invasion, and chemo-resistance by targeting sphingosine-1-phosphate phosphatase 1. | 4 |
| 33125091 | 2020 | Sevoflurane suppresses cell viability and invasion and promotes cell apoptosis in colon cancer by modulating exosome‑mediated circ‑HMGCS1 via the miR‑34a‑5p/SGPP1 axis. | 25 |
| 33125091 | 2020 | Sevoflurane suppresses cell viability and invasion and promotes cell apoptosis in colon cancer by modulating exosome‑mediated circ‑HMGCS1 via the miR‑34a‑5p/SGPP1 axis. | 25 |
| 29375197 | 2017 | Nuclear Translocation of SGPP-1 and Decrease of SGPL-1 Activity Contribute to Sphingolipid Rheostat Regulation of Inflammatory Dendritic Cells. | 6 |
| 29375197 | 2017 | Nuclear Translocation of SGPP-1 and Decrease of SGPL-1 Activity Contribute to Sphingolipid Rheostat Regulation of Inflammatory Dendritic Cells. | 6 |
| 26239167 | 2015 | Inhibition of sphingosine-1-phosphate phosphatase 1 promotes cancer cells migration in gastric cancer: Clinical implications. | 11 |
| 26239167 | 2015 | Inhibition of sphingosine-1-phosphate phosphatase 1 promotes cancer cells migration in gastric cancer: Clinical implications. | 11 |
| 25166914 | 2014 | Tumor suppressor microRNA-27a in colorectal carcinogenesis and progression by targeting SGPP1 and Smad2. | 65 |
| 25166914 | 2014 | Tumor suppressor microRNA-27a in colorectal carcinogenesis and progression by targeting SGPP1 and Smad2. | 65 |
| 24145350 | 2013 | miRNA-95 mediates radioresistance in tumors by targeting the sphingolipid phosphatase SGPP1. | 68 |
| 24145350 | 2013 | miRNA-95 mediates radioresistance in tumors by targeting the sphingolipid phosphatase SGPP1. | 68 |
| 22106015 | 2012 | Sphingosine-1-phosphate is increased in patients with idiopathic pulmonary fibrosis and mediates epithelial to mesenchymal transition. | 77 |
| 22106015 | 2012 | Sphingosine-1-phosphate is increased in patients with idiopathic pulmonary fibrosis and mediates epithelial to mesenchymal transition. | 77 |
| 20798685 | 2011 | Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy. | 76 |
Citation
Dessen P
SGPP1 (sphingosine-1-phosphate phosphatase 1)
Atlas Genet Cytogenet Oncol Haematol. 2015-12-01
Online version: http://atlasgeneticsoncology.org/gene/55542/sgpp1-(sphingosine-1-phosphate-phosphatase-1)
