Identity
HGNC
LOCATION
12q24.11
LOCUSID
ALIAS
CDP2,CUTL2,DEE67,EIEE67
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23316
MIM: 610648
HGNC: 19347
Ensembl: ENSG00000111249
Variants:
dbSNP: 23316
ClinVar: 23316
TCGA: ENSG00000111249
COSMIC: CUX2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000111249 | ENST00000261726 | O14529 |
| ENSG00000111249 | ENST00000397643 | F5GWR6 |
Expression (GTEx)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA445941 | Tuberculosis | Disease | ClinicalAnnotation | associated | PD | ||
| PA451250 | rifampin | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35881915 | 2022 | CUX2/KDM5B/SOX17 Axis Affects the Occurrence and Development of Breast Cancer. | 3 |
| 35881915 | 2022 | CUX2/KDM5B/SOX17 Axis Affects the Occurrence and Development of Breast Cancer. | 3 |
| 33093602 | 2020 | CUX2, BRAP and ALDH2 are associated with metabolic traits in people with excessive alcohol consumption. | 4 |
| 33093602 | 2020 | CUX2, BRAP and ALDH2 are associated with metabolic traits in people with excessive alcohol consumption. | 4 |
| 30720667 | 2019 | Association of FAM65B, AGBL4, and CUX2 genetic polymorphisms with susceptibility to antituberculosis drug-induced hepatotoxicity: validation study in a Chinese Han population. | 2 |
| 30720667 | 2019 | Association of FAM65B, AGBL4, and CUX2 genetic polymorphisms with susceptibility to antituberculosis drug-induced hepatotoxicity: validation study in a Chinese Han population. | 2 |
| 29459676 | 2018 | Genomic Variants in NEURL, GJA1 and CUX2 Significantly Increase Genetic Susceptibility to Atrial Fibrillation. | 8 |
| 29630738 | 2018 | The epilepsy phenotypic spectrum associated with a recurrent CUX2 variant. | 10 |
| 29795476 | 2018 | A recurrent de novo CUX2 missense variant associated with intellectual disability, seizures, and autism spectrum disorder. | 10 |
| 29459676 | 2018 | Genomic Variants in NEURL, GJA1 and CUX2 Significantly Increase Genetic Susceptibility to Atrial Fibrillation. | 8 |
| 29630738 | 2018 | The epilepsy phenotypic spectrum associated with a recurrent CUX2 variant. | 10 |
| 29795476 | 2018 | A recurrent de novo CUX2 missense variant associated with intellectual disability, seizures, and autism spectrum disorder. | 10 |
| 26221032 | 2015 | CUX2 protein functions as an accessory factor in the repair of oxidative DNA damage. | 24 |
| 26221032 | 2015 | CUX2 protein functions as an accessory factor in the repair of oxidative DNA damage. | 24 |
| 19401682 | 2010 | High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility. | 71 |
Citation
Dessen P
CUX2 (cut like homeobox 2)
Atlas Genet Cytogenet Oncol Haematol. 2015-12-01
Online version: http://atlasgeneticsoncology.org/gene/55545/cux2-(cut-like-homeobox-2)
