KIF3C (kinesin family member 3C)

2015-12-01  

Identity

HGNC
LOCATION
2p23.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 3797
MIM: 602845
HGNC: 6321
Ensembl: ENSG00000084731

Variants:

dbSNP: 3797
ClinVar: 3797
TCGA: ENSG00000084731
COSMIC: KIF3C

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000084731ENST00000264712O14782
ENSG00000084731ENST00000264712A2RU78
ENSG00000084731ENST00000405914O14782
ENSG00000084731ENST00000405914A2RU78
ENSG00000084731ENST00000417737F8WER6
ENSG00000084731ENST00000455394F8WAR6

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Cilium AssemblyREACTOMER-HSA-5617833
Intraflagellar transportREACTOMER-HSA-5620924
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
MHC class II antigen presentationREACTOMER-HSA-2132295
HemostasisREACTOMER-HSA-109582
Factors involved in megakaryocyte development and platelet productionREACTOMER-HSA-983231
KinesinsREACTOMER-HSA-983189
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Golgi-to-ER retrograde transportREACTOMER-HSA-8856688
COPI-dependent Golgi-to-ER retrograde trafficREACTOMER-HSA-6811434

References

Pubmed IDYearTitleCitations
377521012023Double heterozygous pathogenic mutations in KIF3C and ZNF513 cause hereditary gingival fibromatosis.0
377521012023Double heterozygous pathogenic mutations in KIF3C and ZNF513 cause hereditary gingival fibromatosis.0
341930182021Kinesin family member 3C (KIF3C) is a novel non-small cell lung cancer (NSCLC) oncogene whose expression is modulated by microRNA-150-5p (miR-150-5p) and microRNA-186-3p (miR-186-3p).5
341930182021Kinesin family member 3C (KIF3C) is a novel non-small cell lung cancer (NSCLC) oncogene whose expression is modulated by microRNA-150-5p (miR-150-5p) and microRNA-186-3p (miR-186-3p).5
320204812020KIF3C is associated with favorable prognosis in glioma patients and may be regulated by PI3K/AKT/mTOR pathway.7
331501782020KIF3C Promotes Proliferation, Migration, and Invasion of Glioma Cells by Activating the PI3K/AKT Pathway and Inducing EMT.12
320204812020KIF3C is associated with favorable prognosis in glioma patients and may be regulated by PI3K/AKT/mTOR pathway.7
331501782020KIF3C Promotes Proliferation, Migration, and Invasion of Glioma Cells by Activating the PI3K/AKT Pathway and Inducing EMT.12
262721842015Suppression of motor protein KIF3C expression inhibits tumor growth and metastasis in breast cancer by inhibiting TGF-β signaling.16
262721842015Suppression of motor protein KIF3C expression inhibits tumor growth and metastasis in breast cancer by inhibiting TGF-β signaling.16
178816552007The fragile X mental retardation protein is a molecular adaptor between the neurospecific KIF3C kinesin and dendritic RNA granules.68
178816552007The fragile X mental retardation protein is a molecular adaptor between the neurospecific KIF3C kinesin and dendritic RNA granules.68

Citation

Dessen P

KIF3C (kinesin family member 3C)

Atlas Genet Cytogenet Oncol Haematol. 2015-12-01

Online version: http://atlasgeneticsoncology.org/gene/55551/kif3c-(kinesin-family-member-3c)