Identity
HGNC
LOCATION
1q22
LOCUSID
ALIAS
CORD10,RP35,SEMAB,SEMB
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 64218
MIM: 607292
HGNC: 10729
Ensembl: ENSG00000196189
Variants:
dbSNP: 64218
ClinVar: 64218
TCGA: ENSG00000196189
COSMIC: SEMA4A
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37205755 | 2023 | Tumor-derived semaphorin 4A improves PD-1-blocking antibody efficacy by enhancing CD8(+) T cell cytotoxicity and proliferation. | 6 |
| 37901456 | 2023 | Semaphorin4A promotes lung cancer by activation of NF-κB pathway mediated by PlexinB1. | 0 |
| 37205755 | 2023 | Tumor-derived semaphorin 4A improves PD-1-blocking antibody efficacy by enhancing CD8(+) T cell cytotoxicity and proliferation. | 6 |
| 37901456 | 2023 | Semaphorin4A promotes lung cancer by activation of NF-κB pathway mediated by PlexinB1. | 0 |
| 35328445 | 2022 | Identifying Function Determining Residues in Neuroimmune Semaphorin 4A. | 2 |
| 35460904 | 2022 | The possible involvement of sema3A and sema4A in the pathogenesis of multiple sclerosis. | 1 |
| 35328445 | 2022 | Identifying Function Determining Residues in Neuroimmune Semaphorin 4A. | 2 |
| 35460904 | 2022 | The possible involvement of sema3A and sema4A in the pathogenesis of multiple sclerosis. | 1 |
| 33460983 | 2021 | Semaphorin 4A restricts tumor progression by inhibiting angiogenesis of oral squamous cell carcinoma cells. | 4 |
| 33460983 | 2021 | Semaphorin 4A restricts tumor progression by inhibiting angiogenesis of oral squamous cell carcinoma cells. | 4 |
| 31876207 | 2020 | T-cell specific upregulation of Sema4A as risk factor for autoimmunity in systemic lupus erythematosus and rheumatoid arthritis. | 1 |
| 32169103 | 2020 | Sema4A is implicated in the acceleration of Th17 cell-mediated neuroinflammation in the effector phase. | 4 |
| 32244055 | 2020 | Semaphorin 4A, 4C, and 4D: Function comparison in the autoimmunity, allergy, and cancer. | 14 |
| 32971928 | 2020 | Semaphorin4A-Plexin D1 Axis Induces Th2 and Th17 While Represses Th1 Skewing in an Autocrine Manner. | 9 |
| 31876207 | 2020 | T-cell specific upregulation of Sema4A as risk factor for autoimmunity in systemic lupus erythematosus and rheumatoid arthritis. | 1 |
Citation
Dessen P
SEMA4A (semaphorin 4A)
Atlas Genet Cytogenet Oncol Haematol. 2015-12-01
Online version: http://atlasgeneticsoncology.org/gene/55553/sema4a-(semaphorin-4a)
