SEMA6A (semaphorin 6A)

2015-12-01  

Identity

HGNC
LOCATION
5q23.1
LOCUSID
ALIAS
HT018,SEMA,SEMA6A1,SEMAQ,VIA
FUSION GENES

Other Information

Locus ID:

NCBI: 57556
MIM: 605885
HGNC: 10738
Ensembl: ENSG00000092421

Variants:

dbSNP: 57556
ClinVar: 57556
TCGA: ENSG00000092421
COSMIC: SEMA6A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000092421ENST00000257414A0A0A0MQU6
ENSG00000092421ENST00000343348Q9H2E6
ENSG00000092421ENST00000503865E9PDV9
ENSG00000092421ENST00000509665D6RCR0
ENSG00000092421ENST00000510263Q9H2E6
ENSG00000092421ENST00000513137B3KU01
ENSG00000092421ENST00000515009D6RAG9
ENSG00000092421ENST00000515129H0Y8V9

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50

Pathways

PathwaySourceExternal ID
Axon guidanceKEGGko04360
Axon guidanceKEGGhsa04360
Developmental BiologyREACTOMER-HSA-1266738
Axon guidanceREACTOMER-HSA-422475
Semaphorin interactionsREACTOMER-HSA-373755
Other semaphorin interactionsREACTOMER-HSA-416700

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
323025242020Genome-Wide CRISPR Screen Identifies Semaphorin 6A and 6B as Receptors for Paeniclostridium sordellii Toxin TcsL.20
323025242020Genome-Wide CRISPR Screen Identifies Semaphorin 6A and 6B as Receptors for Paeniclostridium sordellii Toxin TcsL.20
315115122019In vivo epigenetic editing of Sema6a promoter reverses transcallosal dysconnectivity caused by C11orf46/Arl14ep risk gene.20
315276962019Semaphorin 6A Attenuates the Migration Capability of Lung Cancer Cells via the NRF2/HMOX1 Axis.19
316879472019NEW GENETIC MARKERS ASSOCIATED WITH SUSCEPTIBILITY TO EXFOLIATION SYNDROME AMONG GEORGIAN POPULATION.0
315115122019In vivo epigenetic editing of Sema6a promoter reverses transcallosal dysconnectivity caused by C11orf46/Arl14ep risk gene.20
315276962019Semaphorin 6A Attenuates the Migration Capability of Lung Cancer Cells via the NRF2/HMOX1 Axis.19
316879472019NEW GENETIC MARKERS ASSOCIATED WITH SUSCEPTIBILITY TO EXFOLIATION SYNDROME AMONG GEORGIAN POPULATION.0
277878632017Characterization of Semaphorin 6A-Mediated Effects on Angiogenesis Through Regulation of VEGF Signaling.1
289828522017Suppression of Oral Carcinoma Oncogenic Activity by microRNA-203 via Down-regulation of SEMA6A.12
277878632017Characterization of Semaphorin 6A-Mediated Effects on Angiogenesis Through Regulation of VEGF Signaling.1
289828522017Suppression of Oral Carcinoma Oncogenic Activity by microRNA-203 via Down-regulation of SEMA6A.12
255769232015Sema6A and Mical1 control cell growth and survival of BRAFV600E human melanoma cells.37
260145172015SEMA6A is a prognostic biomarker in glioblastoma.14
255769232015Sema6A and Mical1 control cell growth and survival of BRAFV600E human melanoma cells.37

Citation

Dessen P

SEMA6A (semaphorin 6A)

Atlas Genet Cytogenet Oncol Haematol. 2015-12-01

Online version: http://atlasgeneticsoncology.org/gene/55554/sema6a-(semaphorin-6a)