Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3419
MIM: 601149
HGNC: 5384
Ensembl: ENSG00000166411
Variants:
dbSNP: 3419
ClinVar: 3419
TCGA: ENSG00000166411
COSMIC: IDH3A
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35463978 | 2022 | Subcellular Proteome Analysis Reveals Apoptotic Vulnerability of T-Cell Acute Lymphoblastic Leukemia. | 0 |
| 35463978 | 2022 | Subcellular Proteome Analysis Reveals Apoptotic Vulnerability of T-Cell Acute Lymphoblastic Leukemia. | 0 |
| 34269949 | 2021 | Association between IDH mutational status and tumor-associated epilepsy or venous thromboembolism in patients with grade II and III astrocytoma. | 1 |
| 34269949 | 2021 | Association between IDH mutational status and tumor-associated epilepsy or venous thromboembolism in patients with grade II and III astrocytoma. | 1 |
| 30613765 | 2019 | IDH3α regulates one-carbon metabolism in glioblastoma. | 40 |
| 31012789 | 2019 | A novel missense variant in IDH3A causes autosomal recessive retinitis pigmentosa. | 6 |
| 30613765 | 2019 | IDH3α regulates one-carbon metabolism in glioblastoma. | 40 |
| 31012789 | 2019 | A novel missense variant in IDH3A causes autosomal recessive retinitis pigmentosa. | 6 |
| 25531325 | 2015 | Aberrant IDH3α expression promotes malignant tumor growth by inducing HIF-1-mediated metabolic reprogramming and angiogenesis. | 54 |
| 25531325 | 2015 | Aberrant IDH3α expression promotes malignant tumor growth by inducing HIF-1-mediated metabolic reprogramming and angiogenesis. | 54 |
| 20306291 | 2010 | A three-stage genome-wide association study of general cognitive ability: hunting the small effects. | 40 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 20306291 | 2010 | A three-stage genome-wide association study of general cognitive ability: hunting the small effects. | 40 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 17432878 | 2007 | Role of alpha-Asp181, beta-Asp192, and gamma-Asp190 in the distinctive subunits of human NAD-specific isocitrate dehydrogenase. | 17 |
Citation
Dessen P
IDH3A (isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha)
Atlas Genet Cytogenet Oncol Haematol. 2015-12-01
Online version: http://atlasgeneticsoncology.org/gene/55555/idh3a-(isocitrate-dehydrogenase-(nad(+))-3-catalytic-subunit-alpha)
