Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10123
MIM: 604787
HGNC: 698
Ensembl: ENSG00000188042
Variants:
dbSNP: 10123
ClinVar: 10123
TCGA: ENSG00000188042
COSMIC: ARL4C
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000188042 | ENST00000339728 | P56559 |
| ENSG00000188042 | ENST00000390645 | P56559 |
| ENSG00000188042 | ENST00000390645 | A0A024R4C5 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37141698 | 2023 | Stepwise activation of p63 and the MEK/ERK pathway induces the expression of ARL4C to promote oral squamous cell carcinoma cell proliferation. | 1 |
| 37237373 | 2023 | ARL4C is associated with epithelial-to-mesenchymal transition in colorectal cancer. | 2 |
| 37141698 | 2023 | Stepwise activation of p63 and the MEK/ERK pathway induces the expression of ARL4C to promote oral squamous cell carcinoma cell proliferation. | 1 |
| 37237373 | 2023 | ARL4C is associated with epithelial-to-mesenchymal transition in colorectal cancer. | 2 |
| 34622442 | 2022 | RAF1-MEK/ERK pathway-dependent ARL4C expression promotes ameloblastoma cell proliferation and osteoclast formation. | 14 |
| 35718975 | 2022 | Identification of Neural Progenitor Cell-associated Chemoradiotherapy Resistance Gene Set (ARL4C, MSN, TNFAIP6) for Prognosis of Glioma. | 2 |
| 36366750 | 2022 | ARL4C depletion suppresses the resistance of ovarian cancer to carboplatin by disrupting cholesterol transport and autophagy via notch-RBP-Jκ-H3K4Me3-OSBPL5. | 3 |
| 34622442 | 2022 | RAF1-MEK/ERK pathway-dependent ARL4C expression promotes ameloblastoma cell proliferation and osteoclast formation. | 14 |
| 35718975 | 2022 | Identification of Neural Progenitor Cell-associated Chemoradiotherapy Resistance Gene Set (ARL4C, MSN, TNFAIP6) for Prognosis of Glioma. | 2 |
| 36366750 | 2022 | ARL4C depletion suppresses the resistance of ovarian cancer to carboplatin by disrupting cholesterol transport and autophagy via notch-RBP-Jκ-H3K4Me3-OSBPL5. | 3 |
| 33724652 | 2021 | ARL4C might serve as a prognostic factor and a novel therapeutic target for gastric cancer: bioinformatics analyses and biological experiments. | 6 |
| 33724652 | 2021 | ARL4C might serve as a prognostic factor and a novel therapeutic target for gastric cancer: bioinformatics analyses and biological experiments. | 6 |
| 31925985 | 2020 | ARL4C is associated with initiation and progression of lung adenocarcinoma and represents a therapeutic target. | 15 |
| 31925985 | 2020 | ARL4C is associated with initiation and progression of lung adenocarcinoma and represents a therapeutic target. | 15 |
| 30357833 | 2019 | ARL4C stabilized by AKT/mTOR pathway promotes the invasion of PTEN-deficient primary human glioblastoma. | 17 |
Citation
Dessen P
ARL4C (ADP ribosylation factor like GTPase 4C)
Atlas Genet Cytogenet Oncol Haematol. 2016-01-01
Online version: http://atlasgeneticsoncology.org/gene/55569/arl4c-(adp-ribosylation-factor-like-gtpase-4c)
