Identity
HGNC
LOCATION
2p11.2
LOCUSID
ALIAS
HATH6,bHLHa21
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84913
HGNC: 24126
Ensembl: ENSG00000168874
Variants:
dbSNP: 84913
ClinVar: 84913
TCGA: ENSG00000168874
COSMIC: ATOH8
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000168874 | ENST00000306279 | Q96SQ7 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36626550 | 2023 | ATOH8 binds SMAD3 to induce cellular senescence and prevent Ras-driven malignant transformation. | 3 |
| 37232357 | 2023 | ATOH8 promotes HBV immune tolerance by inhibiting the pyroptotic pathway in hepatocytes. | 0 |
| 38060684 | 2023 | ATOH8 Expression Is Regulated by BMP2 and Plays a Key Role in Human Endometrial Stromal Cell Decidualization. | 1 |
| 36626550 | 2023 | ATOH8 binds SMAD3 to induce cellular senescence and prevent Ras-driven malignant transformation. | 3 |
| 37232357 | 2023 | ATOH8 promotes HBV immune tolerance by inhibiting the pyroptotic pathway in hepatocytes. | 0 |
| 38060684 | 2023 | ATOH8 Expression Is Regulated by BMP2 and Plays a Key Role in Human Endometrial Stromal Cell Decidualization. | 1 |
| 33049034 | 2021 | A novel isoform of ATOH8 promotes the metastasis of breast cancer by regulating RhoC. | 0 |
| 33546582 | 2021 | Long non-coding RNA CIR inhibits chondrogenic differentiation of mesenchymal stem cells by epigenetically suppressing ATOH8 via methyltransferase EZH2. | 12 |
| 33049034 | 2021 | A novel isoform of ATOH8 promotes the metastasis of breast cancer by regulating RhoC. | 0 |
| 33546582 | 2021 | Long non-coding RNA CIR inhibits chondrogenic differentiation of mesenchymal stem cells by epigenetically suppressing ATOH8 via methyltransferase EZH2. | 12 |
| 32000836 | 2020 | Shear stress activates ATOH8 via autocrine VEGF promoting glycolysis dependent-survival of colorectal cancer cells in the circulation. | 24 |
| 32000836 | 2020 | Shear stress activates ATOH8 via autocrine VEGF promoting glycolysis dependent-survival of colorectal cancer cells in the circulation. | 24 |
| 30786928 | 2019 | Lnc-PDZD7 contributes to stemness properties and chemosensitivity in hepatocellular carcinoma through EZH2-mediated ATOH8 transcriptional repression. | 26 |
| 30786928 | 2019 | Lnc-PDZD7 contributes to stemness properties and chemosensitivity in hepatocellular carcinoma through EZH2-mediated ATOH8 transcriptional repression. | 26 |
| 28393252 | 2017 | High expression of atonal homolog 8 predicts a poor clinical outcome in patients with colorectal cancer and contributes to tumor progression. | 10 |
Citation
Dessen P
ATOH8 (atonal bHLH transcription factor 8)
Atlas Genet Cytogenet Oncol Haematol. 2016-01-01
Online version: http://atlasgeneticsoncology.org/gene/55590/atoh8-(atonal-bhlh-transcription-factor-8)
