Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 116443
MIM: 606650
HGNC: 16767
Ensembl: ENSG00000198785
Variants:
dbSNP: 116443
ClinVar: 116443
TCGA: ENSG00000198785
COSMIC: GRIN3A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000198785 | ENST00000361820 | Q8TCU5 |
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA445876 | Tobacco Use Disorder | Disease | ClinicalAnnotation | associated | 20084518 | ||
| PA450626 | nicotine | Chemical | ClinicalAnnotation | associated | 20084518 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36898314 | 2023 | Correlations between GRIN2B and GRIN3A gene polymorphisms and postpartum depressive symptoms in Chinese parturients undergoing cesarean section: A prospective cohort study. | 1 |
| 37248111 | 2023 | Excitatory GluN1/GluN3A glycine receptors (eGlyRs) in brain signaling. | 3 |
| 36898314 | 2023 | Correlations between GRIN2B and GRIN3A gene polymorphisms and postpartum depressive symptoms in Chinese parturients undergoing cesarean section: A prospective cohort study. | 1 |
| 37248111 | 2023 | Excitatory GluN1/GluN3A glycine receptors (eGlyRs) in brain signaling. | 3 |
| 34151525 | 2022 | Pathogenesis of sporadic Alzheimer's disease by deficiency of NMDA receptor subunit GluN3A. | 12 |
| 34151525 | 2022 | Pathogenesis of sporadic Alzheimer's disease by deficiency of NMDA receptor subunit GluN3A. | 12 |
| 30741440 | 2020 | Demonstration of critical role of GRIN3A in nicotine dependence through both genetic association and molecular functional studies. | 6 |
| 30741440 | 2020 | Demonstration of critical role of GRIN3A in nicotine dependence through both genetic association and molecular functional studies. | 6 |
| 29678681 | 2019 | Genome-wide meta-analysis identifies novel gender specific loci associated with thyroid antibodies level in Croatians. | 5 |
| 31444392 | 2019 | Structural features in the glycine-binding sites of the GluN1 and GluN3A subunits regulate the surface delivery of NMDA receptors. | 13 |
| 29678681 | 2019 | Genome-wide meta-analysis identifies novel gender specific loci associated with thyroid antibodies level in Croatians. | 5 |
| 31444392 | 2019 | Structural features in the glycine-binding sites of the GluN1 and GluN3A subunits regulate the surface delivery of NMDA receptors. | 13 |
| 27542340 | 2016 | Association between genetic variations of NMDA receptor NR3 subfamily genes and heroin addiction in male Han Chinese. | 5 |
| 27558536 | 2016 | Emerging roles of GluN3-containing NMDA receptors in the CNS. | 84 |
| 27840953 | 2016 | GRIN3A and MAPT stimulate nerve overgrowth in macrodactyly. | 3 |
Citation
Dessen P
GRIN3A (glutamate ionotropic receptor NMDA type subunit 3A)
Atlas Genet Cytogenet Oncol Haematol. 2016-01-01
Online version: http://atlasgeneticsoncology.org/gene/55598/grin3a-(glutamate-ionotropic-receptor-nmda-type-subunit-3a)
