RSL1D1 (ribosomal L1 domain containing 1)

2016-01-01  

Identity

HGNC
LOCATION
16p13.13
LOCUSID
ALIAS
CSIG,L12,PBK1,UTP30
FUSION GENES

Other Information

Locus ID:

NCBI: 26156
MIM: 615874
HGNC: 24534
Ensembl: ENSG00000171490

Variants:

dbSNP: 26156
ClinVar: 26156
TCGA: ENSG00000171490
COSMIC: RSL1D1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171490ENST00000355674J3QSV6
ENSG00000171490ENST00000396503J3KPU7
ENSG00000171490ENST00000570767I3L2F2
ENSG00000171490ENST00000571133O76021
ENSG00000171490ENST00000571988I3L3C4
ENSG00000171490ENST00000572090I3L1A3
ENSG00000171490ENST00000573029I3L4T8
ENSG00000171490ENST00000573251I3L3U9
ENSG00000171490ENST00000573618I3L1Y4
ENSG00000171490ENST00000573791I3L234

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
369133752023RSL1D1 knockdown induces ferroptosis and mediates ferrous iron accumulation in senescent cells by inhibiting FTH1 mRNA stability.1
369133752023RSL1D1 knockdown induces ferroptosis and mediates ferrous iron accumulation in senescent cells by inhibiting FTH1 mRNA stability.1
350131342022RSL1D1 promotes the progression of colorectal cancer through RAN-mediated autophagy suppression.6
355972992022Mutations in DNA binding domain of p53 impede RSL1D1-p53 interaction to escape from degradation in human colorectal cancer cells.1
350131342022RSL1D1 promotes the progression of colorectal cancer through RAN-mediated autophagy suppression.6
355972992022Mutations in DNA binding domain of p53 impede RSL1D1-p53 interaction to escape from degradation in human colorectal cancer cells.1
343624242021Ribosomal L1 domain-containing protein 1 coordinates with HDM2 to negatively regulate p53 in human colorectal Cancer cells.3
343624242021Ribosomal L1 domain-containing protein 1 coordinates with HDM2 to negatively regulate p53 in human colorectal Cancer cells.3
302018052018The Cellular Senescence-Inhibited Gene Is Essential for PPM1A Myristoylation To Modulate Transforming Growth Factor β Signaling.4
302018052018The Cellular Senescence-Inhibited Gene Is Essential for PPM1A Myristoylation To Modulate Transforming Growth Factor β Signaling.4
278119662016Regulation of the MDM2-p53 pathway by the nucleolar protein CSIG in response to nucleolar stress.14
278119662016Regulation of the MDM2-p53 pathway by the nucleolar protein CSIG in response to nucleolar stress.14
257493812015CSIG promotes hepatocellular carcinoma proliferation by activating c-MYC expression.14
257493812015CSIG promotes hepatocellular carcinoma proliferation by activating c-MYC expression.14
186786452008CSIG inhibits PTEN translation in replicative senescence.29

Citation

Dessen P

RSL1D1 (ribosomal L1 domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-01-01

Online version: http://atlasgeneticsoncology.org/gene/55605/rsl1d1-(ribosomal-l1-domain-containing-1)