VSTM1 (V-set and transmembrane domain containing 1)

2016-01-01  

Identity

HGNC
LOCATION
19q13.42
LOCUSID
ALIAS
SIRL-1,SIRL1,UNQ3033

Other Information

Locus ID:

NCBI: 284415
MIM: 616804
HGNC: 29455
Ensembl: ENSG00000189068

Variants:

dbSNP: 284415
ClinVar: 284415
TCGA: ENSG00000189068
COSMIC: VSTM1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000189068ENST00000338372Q6UX27
ENSG00000189068ENST00000366170D2DJS5
ENSG00000189068ENST00000376626Q6UX27
ENSG00000189068ENST00000419106H7C340
ENSG00000189068ENST00000425006G8JLN4
ENSG00000189068ENST00000447872Q6UX27
ENSG00000189068ENST00000645936A0A2R8Y636

Expression (GTEx)

0
5
10
15
20
25
30

References

Pubmed IDYearTitleCitations
379358372024New insights into the role of the immune inhibitory receptor VSTM1 in autoimmune disease.0
379358372024New insights into the role of the immune inhibitory receptor VSTM1 in autoimmune disease.0
370532482023VSTM1-v2 does not drive human Th17 cell differentiation: A replication study.0
377373092023Oxidized galectin-1 in SLE fails to bind the inhibitory receptor VSTM1 and increases reactive oxygen species levels in neutrophils.2
370532482023VSTM1-v2 does not drive human Th17 cell differentiation: A replication study.0
377373092023Oxidized galectin-1 in SLE fails to bind the inhibitory receptor VSTM1 and increases reactive oxygen species levels in neutrophils.2
341459092021Recognition of S100 proteins by Signal Inhibitory Receptor on Leukocytes-1 negatively regulates human neutrophils.8
341459092021Recognition of S100 proteins by Signal Inhibitory Receptor on Leukocytes-1 negatively regulates human neutrophils.8
318435672020Signal inhibitory receptor on leukocytes (SIRL)-1 and leukocyte- associated immunoglobulin-like receptor (LAIR)-1 regulate neutrophil function in infants.8
329421892020Signal Inhibitory Receptor on Leukocytes-1 is highly expressed on lung monocytes, but absent on mononuclear phagocytes in skin and colon.2
318435672020Signal inhibitory receptor on leukocytes (SIRL)-1 and leukocyte- associated immunoglobulin-like receptor (LAIR)-1 regulate neutrophil function in infants.8
329421892020Signal Inhibitory Receptor on Leukocytes-1 is highly expressed on lung monocytes, but absent on mononuclear phagocytes in skin and colon.2
282194442017A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus.15
282194442017A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus.15
267600412016Expression of VSTM1-v2 Is Increased in Peripheral Blood Mononuclear Cells from Patients with Rheumatoid Arthritis and Is Correlated with Disease Activity.6

Citation

Dessen P

VSTM1 (V-set and transmembrane domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-01-01

Online version: http://atlasgeneticsoncology.org/gene/55608/vstm1-(v-set-and-transmembrane-domain-containing-1)