ZNF677 (zinc finger protein 677)

2016-01-01  

Identity

HGNC
ZNF677
LOCATION
19q13.42
LOCUSID
342926
ALIAS
-

Other Information

Locus ID:

NCBI: 342926
HGNC: 28730
Ensembl: ENSG00000197928

Variants:

dbSNP: 342926
ClinVar: 342926
TCGA: ENSG00000197928
COSMIC: ZNF677

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197928ENST00000333952Q86XU0
ENSG00000197928ENST00000594517M0R297
ENSG00000197928ENST00000594681M0R1V2
ENSG00000197928ENST00000598513Q86XU0
ENSG00000197928ENST00000598806M0R079
ENSG00000197928ENST00000599012M0QYA4
ENSG00000197928ENST00000601413M0R0I7
ENSG00000197928ENST00000601828M0R0I7

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
371297992023ZNF677 inhibits oral squamous cell carcinoma growth and tumor stemness by regulating FOXO3a.0
371297992023ZNF677 inhibits oral squamous cell carcinoma growth and tumor stemness by regulating FOXO3a.0
351646602022Overexpression of zinc-finger protein 677 inhibits proliferation and invasion by and induces apoptosis in clear cell renal cell carcinoma.1
356782312022ZNF677 suppresses renal cell carcinoma progression through N6-methyladenosine and transcriptional repression of CDKN3.20
351646602022Overexpression of zinc-finger protein 677 inhibits proliferation and invasion by and induces apoptosis in clear cell renal cell carcinoma.1
356782312022ZNF677 suppresses renal cell carcinoma progression through N6-methyladenosine and transcriptional repression of CDKN3.20
341713552021ZNF677 downregulation by promoter hypermethylation as a driver event through gastric tumorigenesis.3
343605992021Loss of ZNF677 Expression Is an Independent Predictor for Distant Metastasis in Middle Eastern Papillary Thyroid Carcinoma Patients.4
347857642021Loss of ZNF677 expression is a predictive biomarker for lymph node metastasis in Middle Eastern Colorectal Cancer.2
341713552021ZNF677 downregulation by promoter hypermethylation as a driver event through gastric tumorigenesis.3
343605992021Loss of ZNF677 Expression Is an Independent Predictor for Distant Metastasis in Middle Eastern Papillary Thyroid Carcinoma Patients.4
347857642021Loss of ZNF677 expression is a predictive biomarker for lymph node metastasis in Middle Eastern Colorectal Cancer.2
299972312018ZNF677 Suppresses Akt Phosphorylation and Tumorigenesis in Thyroid Cancer.32
299972312018ZNF677 Suppresses Akt Phosphorylation and Tumorigenesis in Thyroid Cancer.32
255044382015DNA methylation transcriptionally regulates the putative tumor cell growth suppressor ZNF677 in non-small cell lung cancers.15

Citation

Dessen P

ZNF677 (zinc finger protein 677)

Atlas Genet Cytogenet Oncol Haematol. 2016-01-01

Online version: http://atlasgeneticsoncology.org/gene/55610/znf677-(zinc-finger-protein-677)